Cytoxic resveratrol oligomers from the tree bark of Dipterocarpus hasseltii

[No Value] Muhtadi; E.H. Hakim; L.D. Juliawaty; Y.M. Syah; S.A. Achmad; J. Latip; Emilio Ghisalberti

doi:10.1016/j.fitote.2006.07.004

Cytoxic resveratrol oligomers from the tree bark of Dipterocarpus hasseltii

[No Value] Muhtadi, E.H. Hakim, L.D. Juliawaty, Y.M. Syah, S.A. Achmad, J. Latip, Emilio Ghisalberti

School of Molecular Sciences

Research output: Contribution to journal › Article

40 Citations (Scopus)

Abstract

A new resveratrol tetramer, named diptoindonesin E, was isolated from the acetone extract of the tree bark of Dipterocarpus hasseltii, together with five known resveratrol oligomers (-)-epsilon-viniferin, laevifonol, (-)-alpha-viniferin, vaticanol B, (-)-hopeaphenol, and a coumarin, scopoletin. The structures of these compounds were determined from spectroscopic evidence. Cytotoxicity test of the isolated compounds showed that hopeaphenol strongly inhibited murine leukemia P-388 cells. (c) 2006 Elsevier B.V. All rights reserved.

Original language	English
Pages (from-to)	550-555
Journal	Fitoterapia
Volume	77
Issue number	7-8
DOIs	https://doi.org/10.1016/j.fitote.2006.07.004
Publication status	Published - 2006

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Muhtadi, N. V., Hakim, E. H., Juliawaty, L. D., Syah, Y. M., Achmad, S. A., Latip, J., & Ghisalberti, E. (2006). Cytoxic resveratrol oligomers from the tree bark of Dipterocarpus hasseltii. Fitoterapia, 77(7-8), 550-555. https://doi.org/10.1016/j.fitote.2006.07.004

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title = "Cytoxic resveratrol oligomers from the tree bark of Dipterocarpus hasseltii",

abstract = "A new resveratrol tetramer, named diptoindonesin E, was isolated from the acetone extract of the tree bark of Dipterocarpus hasseltii, together with five known resveratrol oligomers (-)-epsilon-viniferin, laevifonol, (-)-alpha-viniferin, vaticanol B, (-)-hopeaphenol, and a coumarin, scopoletin. The structures of these compounds were determined from spectroscopic evidence. Cytotoxicity test of the isolated compounds showed that hopeaphenol strongly inhibited murine leukemia P-388 cells. (c) 2006 Elsevier B.V. All rights reserved.",

author = "Muhtadi, {[No Value]} and E.H. Hakim and L.D. Juliawaty and Y.M. Syah and S.A. Achmad and J. Latip and Emilio Ghisalberti",

year = "2006",

doi = "10.1016/j.fitote.2006.07.004",

language = "English",

volume = "77",

pages = "550--555",

journal = "Ghisalberti, E.L., The Goodeniaceae",

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T1 - Cytoxic resveratrol oligomers from the tree bark of Dipterocarpus hasseltii

AU - Muhtadi, [No Value]

AU - Hakim, E.H.

AU - Juliawaty, L.D.

AU - Syah, Y.M.

AU - Achmad, S.A.

AU - Latip, J.

AU - Ghisalberti, Emilio

PY - 2006

Y1 - 2006

N2 - A new resveratrol tetramer, named diptoindonesin E, was isolated from the acetone extract of the tree bark of Dipterocarpus hasseltii, together with five known resveratrol oligomers (-)-epsilon-viniferin, laevifonol, (-)-alpha-viniferin, vaticanol B, (-)-hopeaphenol, and a coumarin, scopoletin. The structures of these compounds were determined from spectroscopic evidence. Cytotoxicity test of the isolated compounds showed that hopeaphenol strongly inhibited murine leukemia P-388 cells. (c) 2006 Elsevier B.V. All rights reserved.

AB - A new resveratrol tetramer, named diptoindonesin E, was isolated from the acetone extract of the tree bark of Dipterocarpus hasseltii, together with five known resveratrol oligomers (-)-epsilon-viniferin, laevifonol, (-)-alpha-viniferin, vaticanol B, (-)-hopeaphenol, and a coumarin, scopoletin. The structures of these compounds were determined from spectroscopic evidence. Cytotoxicity test of the isolated compounds showed that hopeaphenol strongly inhibited murine leukemia P-388 cells. (c) 2006 Elsevier B.V. All rights reserved.

U2 - 10.1016/j.fitote.2006.07.004

DO - 10.1016/j.fitote.2006.07.004

M3 - Article

VL - 77

SP - 550

EP - 555

JO - Ghisalberti, E.L., The Goodeniaceae

JF - Ghisalberti, E.L., The Goodeniaceae

SN - 1971-551X

IS - 7-8

ER -

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10.1016/j.fitote.2006.07.004