Cyclin-dependent kinase E1 (CDKE1) provides a cellular switch in plants between growth and stress responses

Sophia Ng, Estelle Giraud, Owen Duncan, Simon Law, Yanhui Wang, Lin Xu, Reena Narsai, Christopher Carrie, Hayden Walker, D.A. Day, N.E. Blanco, A. Strand, James Whelan, Aneta Ivanova

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Abstract

Background: Mitochondria send signals to the nucleus to modulate gene expression when mitochondrial function is perturbed. Results: Cyclin-dependent kinase E1 (CDKE1) was identified as an essential component in regulation of responses to perturbation of mitochondrial electron transport. Conclusion: Mitochondrial regulation is integrated with growth, energy, and other cellular stress signaling pathways. Significance: The identification of a molecular link between mitochondrial retrograde regulation and growth and stress signaling pathways. © 2013 by The American Society for Biochemistry and Molecular Biology, Inc.
Original languageEnglish
Pages (from-to)3449-3459
JournalJournal of Biological Chemistry
Volume288
Issue number5
DOIs
Publication statusPublished - 2013

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    Ng, S., Giraud, E., Duncan, O., Law, S., Wang, Y., Xu, L., Narsai, R., Carrie, C., Walker, H., Day, D. A., Blanco, N. E., Strand, A., Whelan, J., & Ivanova, A. (2013). Cyclin-dependent kinase E1 (CDKE1) provides a cellular switch in plants between growth and stress responses. Journal of Biological Chemistry, 288(5), 3449-3459. https://doi.org/10.1074/jbc.M112.416727