Abstract
© Copyright 2016 Wolters Kluwer Health, Inc. All rights reserved.Malignant melanoma is a common source of cutaneous metastases and can occasionally adopt a histological appearance which mimics a primary melanocytic lesion, either benign or malignant. The authors describe a case of new cutaneous deposits of metastatic melanoma in a 70-year-old woman with a prominent admixed lymphocytic infiltrate, imparting a striking resemblance to a halo nevus. The authors believe this appearance was a direct reflection of treatment with pembrolizumab, a humanized antibody against the immune checkpoint inhibitor programmed death-1. With increasing use of immune-modulating drugs, this potential histological mimic may be seen more frequently in the future.
Original language | English |
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Pages (from-to) | e159-e162 |
Journal | American Journal of Dermatopathology |
Volume | 38 |
Issue number | 12 |
DOIs | |
Publication status | Published - 2016 |