Bronchiolitis is a recognized syndrome seen in infants following viral infections. The pattern is different in different countries related to the socio-economic conditions. A sequel that needs to be addressed is post-viral wheeze. Oxygen is the major beneficial pharmacological agent. Bronchodilators may be effective in some. There is a role for Palivizumab and Montelukast in selected infants. It is essential to define the right drug for the right patient at the right dose and the right time. (C) 2006 Elsevier Ltd. All rights reserved.