Curcumin and cognition: A randomised, placebo-controlled, double-blind study of community-dwelling older adults

S.R. Rainey-Smith, B.M. Brown, H.R. Sohrabi, T. Shah, K.G. Goozee, V.B. Gupta, Ralph N. Martins

    Research output: Contribution to journalArticle

    65 Citations (Scopus)

    Abstract

    © The Authors 2016.Curcumin therapy in animals has produced positive cognitive and behavioural outcomes; results of human trials, however, have been inconsistent. In this study, we report the results of a 12-month, randomised, placebo-controlled, double-blind study that investigated the ability of a curcumin formulation to prevent cognitive decline in a population of community-dwelling older adults. Individuals (n 96) ingested either placebo or 1500 mg/d BiocurcumaxTM for 12 months. A battery of clinical and cognitive measures was administered at baseline and at the 6-month and 12-month follow-up assessments. A significant time×treatment group interaction was observed for the Montreal Cognitive Assessment (repeated-measures analysis; time×treatment; F=3·85, P
    Original languageEnglish
    Pages (from-to)2106-2113
    Number of pages8
    JournalBritish Journal of Nutrition
    Volume115
    Issue number12
    DOIs
    Publication statusPublished - 2016

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