TY - JOUR
T1 - Curcumin and cognition: A randomised, placebo-controlled, double-blind study of community-dwelling older adults
AU - Rainey-Smith, S.R.
AU - Brown, B.M.
AU - Sohrabi, H.R.
AU - Shah, T.
AU - Goozee, K.G.
AU - Gupta, V.B.
AU - Martins, Ralph N.
PY - 2016/6/28
Y1 - 2016/6/28
N2 - © The Authors 2016.Curcumin therapy in animals has produced positive cognitive and behavioural outcomes; results of human trials, however, have been inconsistent. In this study, we report the results of a 12-month, randomised, placebo-controlled, double-blind study that investigated the ability of a curcumin formulation to prevent cognitive decline in a population of community-dwelling older adults. Individuals (n 96) ingested either placebo or 1500 mg/d BiocurcumaxTM for 12 months. A battery of clinical and cognitive measures was administered at baseline and at the 6-month and 12-month follow-up assessments. A significant time×treatment group interaction was observed for the Montreal Cognitive Assessment (repeated-measures analysis; time×treatment; F=3·85, P
AB - © The Authors 2016.Curcumin therapy in animals has produced positive cognitive and behavioural outcomes; results of human trials, however, have been inconsistent. In this study, we report the results of a 12-month, randomised, placebo-controlled, double-blind study that investigated the ability of a curcumin formulation to prevent cognitive decline in a population of community-dwelling older adults. Individuals (n 96) ingested either placebo or 1500 mg/d BiocurcumaxTM for 12 months. A battery of clinical and cognitive measures was administered at baseline and at the 6-month and 12-month follow-up assessments. A significant time×treatment group interaction was observed for the Montreal Cognitive Assessment (repeated-measures analysis; time×treatment; F=3·85, P
U2 - 10.1017/S0007114516001203
DO - 10.1017/S0007114516001203
M3 - Article
C2 - 27102361
SN - 0007-1145
VL - 115
SP - 2106
EP - 2113
JO - British Journal of Nutrition
JF - British Journal of Nutrition
IS - 12
ER -