Abstract
| Original language | English |
|---|---|
| Pages (from-to) | on-line |
| Journal | European Journal of Applied Physiology |
| Volume | 106 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2009 |
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Cumulative effects of consecutive running sessions on hemolysis, inflammation and hepcidin activity. / Peeling, Peter; Dawson, Brian; Goodman, C.; Landers, Grant; Wiegerinck, E.T.; Swinkels, D.W.; Trinder, Debbie.
In: European Journal of Applied Physiology, Vol. 106, No. 1, 2009, p. on-line.Research output: Contribution to journal › Article
TY - JOUR
T1 - Cumulative effects of consecutive running sessions on hemolysis, inflammation and hepcidin activity
AU - Peeling, Peter
AU - Dawson, Brian
AU - Goodman, C.
AU - Landers, Grant
AU - Wiegerinck, E.T.
AU - Swinkels, D.W.
AU - Trinder, Debbie
PY - 2009
Y1 - 2009
N2 - The effect of two running sessions completedwithin a 12-h period on hemolysis, inflammation, and hepcidinactivity in endurance athletes was investigated. Tenmales completed two experimental trials in a randomized,counterbalanced order. The two trials included (a) a onerunning-session trial (T1) including 10 9 1 km intervalrepeats (90% peak _V O2 velocity), and (b) a two-runningsessiontrial (T2), comprising a continuous 10-km run (70%peak _V O2 velocity), and a 10 9 1 kminterval run (90% peak_VO2 velocity) completed 12 h later. Interleukin-6 (IL-6),free hemoglobin (Hb), haptoglobin (Hp), iron, ferritin, andhepcidin were assessed post-exercise. After the T1 and T2interval runs, free Hb was significantly increased and Hpsignificantly decreased (p B 0.05), with a cumulative effectshown in T2 after the second run (p B 0.05). The IL-6, serumiron, ferritin, and hepcidin activity were increased after eachrunning session (p B 0.05), with no cumulative effect in T2.In conclusion, a cumulative effect of two running sessions onhemolysis was shown, but no similar effect with inflammationand hepcidin activity was evident.
AB - The effect of two running sessions completedwithin a 12-h period on hemolysis, inflammation, and hepcidinactivity in endurance athletes was investigated. Tenmales completed two experimental trials in a randomized,counterbalanced order. The two trials included (a) a onerunning-session trial (T1) including 10 9 1 km intervalrepeats (90% peak _V O2 velocity), and (b) a two-runningsessiontrial (T2), comprising a continuous 10-km run (70%peak _V O2 velocity), and a 10 9 1 kminterval run (90% peak_VO2 velocity) completed 12 h later. Interleukin-6 (IL-6),free hemoglobin (Hb), haptoglobin (Hp), iron, ferritin, andhepcidin were assessed post-exercise. After the T1 and T2interval runs, free Hb was significantly increased and Hpsignificantly decreased (p B 0.05), with a cumulative effectshown in T2 after the second run (p B 0.05). The IL-6, serumiron, ferritin, and hepcidin activity were increased after eachrunning session (p B 0.05), with no cumulative effect in T2.In conclusion, a cumulative effect of two running sessions onhemolysis was shown, but no similar effect with inflammationand hepcidin activity was evident.
U2 - 10.1007/s00421-009-0988-7
DO - 10.1007/s00421-009-0988-7
M3 - Article
VL - 106
SP - on-line
JO - European Journal of Applied Physiology
JF - European Journal of Applied Physiology
SN - 1439-6319
IS - 1
ER -