Culture-positive urinary tract infection following micturating cystourethrogram in children

Simeon Ngweso, Munyaradzi Nyandoro, Tatenda Nzenza, Ting Yi Cheow, Fiona Bettenay, Andrew Barker, Japinder Khosa, Naeem Samnakay

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To determine the incidence of culture-positive urinary tract infection (UTI) after micturating cystourethrogram (MCUG). We further wanted to identify risk factors for developing a culture-positive UTI following MCUG. Methods: A retrospective review of the available medical records of 500 paediatric patients who underwent MCUG in Perth, Western Australia was performed. Results: Seven (1.4%) patients comprised of four females and three males developed a febrile, culture-positive UTI within 14 days following MCUG. Significant association was found for female patients, patients with neurogenic bladder, and patients with previous culture-positive UTI as developing a culture-positive UTI following MCUG. Multivariate logistic regression determined that patients were more likely to develop culture-positive UTI within 14 days following MCUG if they had a known history of UTI (odds ratio: 5.0, 95% confidence interval: 1.5–17.3, p=0.010) or had a neurogenic bladder (odds ratio: 4.2, 95% confidence interval: 1.0–17.9, p=0.049). Conclusion: The incidence of patients who developed a febrile, culture-positive UTI following MCUG was low at 1.4%. Statistically significant and independent associations for the development of culture positive UTI were found in patients with neurogenic bladder and patients with previous culture-positive UTI. Further prospective studies are necessary to determine necessity of prophylactic antibiotics for high risk patients, e.g., patients with neurogenic bladder or previous culture-positive UTI.

Original languageEnglish
Pages (from-to)329-333
Number of pages5
JournalAsian Journal of Urology
Volume9
Issue number3
Early online date2022
DOIs
Publication statusPublished - Jul 2022

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