Cranking the Immunologic Engine with Chemotherapy:Using Context to Drive Tumor Antigen Cross-Presentation toward Useful Antitumor Immunity

Robbert Van Der Most, Andrew Currie, Bruce Robinson, Richard Lake

Research output: Contribution to journalArticlepeer-review

78 Citations (Scopus)

Abstract

This review shows how tumor antigen cross-presentation is affected by the major therapeutic modalities including chemotherapy, radiotherapy, and surgery. We argue that this process could affect the way that a tumor works as its own cellular vaccine, and that it is differentially modulated by the choice of treatment.
Original languageEnglish
Pages (from-to)601-604
JournalCancer Research
Volume66
Issue number2
DOIs
Publication statusPublished - 2006

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