This review shows how tumor antigen cross-presentation is affected by the major therapeutic modalities including chemotherapy, radiotherapy, and surgery. We argue that this process could affect the way that a tumor works as its own cellular vaccine, and that it is differentially modulated by the choice of treatment.
Van Der Most, R., Currie, A., Robinson, B., & Lake, R. (2006). Cranking the Immunologic Engine with Chemotherapy:Using Context to Drive Tumor Antigen Cross-Presentation toward Useful Antitumor Immunity. Cancer Research, 66(2), 601-604. https://doi.org/10.1158/0008-5472.CAN-05-2967