Cranking the Immunologic Engine with Chemotherapy:Using Context to Drive Tumor Antigen Cross-Presentation toward Useful Antitumor Immunity

Robbert Van Der Most; Andrew Currie; Bruce Robinson; Richard Lake

doi:10.1158/0008-5472.CAN-05-2967

Cranking the Immunologic Engine with Chemotherapy:Using Context to Drive Tumor Antigen Cross-Presentation toward Useful Antitumor Immunity

Robbert Van Der Most, Andrew Currie, Bruce Robinson, Richard Lake

Research output: Contribution to journal › Article › peer-review

87 Citations (Scopus)

Abstract

This review shows how tumor antigen cross-presentation is affected by the major therapeutic modalities including chemotherapy, radiotherapy, and surgery. We argue that this process could affect the way that a tumor works as its own cellular vaccine, and that it is differentially modulated by the choice of treatment.

Original language	English
Pages (from-to)	601-604
Journal	Cancer Research
Volume	66
Issue number	2
DOIs	https://doi.org/10.1158/0008-5472.CAN-05-2967
Publication status	Published - 2006

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10.1158/0008-5472.CAN-05-2967

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title = "Cranking the Immunologic Engine with Chemotherapy:Using Context to Drive Tumor Antigen Cross-Presentation toward Useful Antitumor Immunity",

abstract = "This review shows how tumor antigen cross-presentation is affected by the major therapeutic modalities including chemotherapy, radiotherapy, and surgery. We argue that this process could affect the way that a tumor works as its own cellular vaccine, and that it is differentially modulated by the choice of treatment.",

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Cranking the Immunologic Engine with Chemotherapy:Using Context to Drive Tumor Antigen Cross-Presentation toward Useful Antitumor Immunity

Abstract

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