Cranial CT scan appearances that correlate with patient outcome in acute stroke

S J Davis, G J Hankey, E G Stewart-Wynne, T M Chakera

    Research output: Contribution to journalArticle

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    Abstract

    Certain clinical features are known to correlate with patient outcome in acute stroke, but the potential of cranial CT scan as an aid to predicting recovery after stroke remains unclear. In a prospective study, 178 acute stroke patients admitted to Royal Perth Hospital were assessed by 4 neurologists; 150 cranial CT scans were performed and these were reviewed by an independent radiologist. CT lesion characteristics were cross-tabulated against clinical indices of patient outcome. Lesions greater than 50 cm3 in volume were associated with a 23% mortality compared to a 5% mortality for lesions smaller than 50 cm3. The mortality rate from intracerebral haemorrhage was 25% compared to 9% for other disease. Of patients whose CT scan showed a mass effect, 35% had an altered mental state at discharge compared to only 2% of those without a mass effect. Of the patients with deep white matter lesions, 35% had an altered mental state at discharge compared to only 13% of patients with lesions in other sites, and only 50% were discharged home compared to 77% of patients with lesions in other sites. CT scan features that correlated significantly with a poor outcome following acute stroke were large lesion size, intracerebral haemorrhage, mass effect and deep white matter lesions.

    Original languageEnglish
    Pages (from-to)71-4
    Number of pages4
    JournalClinical and experimental neurology
    Volume23
    Publication statusPublished - 1987

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    Stroke
    Cerebral Hemorrhage
    Mortality
    Prospective Studies
    White Matter

    Cite this

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    title = "Cranial CT scan appearances that correlate with patient outcome in acute stroke",
    abstract = "Certain clinical features are known to correlate with patient outcome in acute stroke, but the potential of cranial CT scan as an aid to predicting recovery after stroke remains unclear. In a prospective study, 178 acute stroke patients admitted to Royal Perth Hospital were assessed by 4 neurologists; 150 cranial CT scans were performed and these were reviewed by an independent radiologist. CT lesion characteristics were cross-tabulated against clinical indices of patient outcome. Lesions greater than 50 cm3 in volume were associated with a 23{\%} mortality compared to a 5{\%} mortality for lesions smaller than 50 cm3. The mortality rate from intracerebral haemorrhage was 25{\%} compared to 9{\%} for other disease. Of patients whose CT scan showed a mass effect, 35{\%} had an altered mental state at discharge compared to only 2{\%} of those without a mass effect. Of the patients with deep white matter lesions, 35{\%} had an altered mental state at discharge compared to only 13{\%} of patients with lesions in other sites, and only 50{\%} were discharged home compared to 77{\%} of patients with lesions in other sites. CT scan features that correlated significantly with a poor outcome following acute stroke were large lesion size, intracerebral haemorrhage, mass effect and deep white matter lesions.",
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    author = "Davis, {S J} and Hankey, {G J} and Stewart-Wynne, {E G} and Chakera, {T M}",
    year = "1987",
    language = "English",
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    Cranial CT scan appearances that correlate with patient outcome in acute stroke. / Davis, S J; Hankey, G J; Stewart-Wynne, E G; Chakera, T M.

    In: Clinical and experimental neurology, Vol. 23, 1987, p. 71-4.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Cranial CT scan appearances that correlate with patient outcome in acute stroke

    AU - Davis, S J

    AU - Hankey, G J

    AU - Stewart-Wynne, E G

    AU - Chakera, T M

    PY - 1987

    Y1 - 1987

    N2 - Certain clinical features are known to correlate with patient outcome in acute stroke, but the potential of cranial CT scan as an aid to predicting recovery after stroke remains unclear. In a prospective study, 178 acute stroke patients admitted to Royal Perth Hospital were assessed by 4 neurologists; 150 cranial CT scans were performed and these were reviewed by an independent radiologist. CT lesion characteristics were cross-tabulated against clinical indices of patient outcome. Lesions greater than 50 cm3 in volume were associated with a 23% mortality compared to a 5% mortality for lesions smaller than 50 cm3. The mortality rate from intracerebral haemorrhage was 25% compared to 9% for other disease. Of patients whose CT scan showed a mass effect, 35% had an altered mental state at discharge compared to only 2% of those without a mass effect. Of the patients with deep white matter lesions, 35% had an altered mental state at discharge compared to only 13% of patients with lesions in other sites, and only 50% were discharged home compared to 77% of patients with lesions in other sites. CT scan features that correlated significantly with a poor outcome following acute stroke were large lesion size, intracerebral haemorrhage, mass effect and deep white matter lesions.

    AB - Certain clinical features are known to correlate with patient outcome in acute stroke, but the potential of cranial CT scan as an aid to predicting recovery after stroke remains unclear. In a prospective study, 178 acute stroke patients admitted to Royal Perth Hospital were assessed by 4 neurologists; 150 cranial CT scans were performed and these were reviewed by an independent radiologist. CT lesion characteristics were cross-tabulated against clinical indices of patient outcome. Lesions greater than 50 cm3 in volume were associated with a 23% mortality compared to a 5% mortality for lesions smaller than 50 cm3. The mortality rate from intracerebral haemorrhage was 25% compared to 9% for other disease. Of patients whose CT scan showed a mass effect, 35% had an altered mental state at discharge compared to only 2% of those without a mass effect. Of the patients with deep white matter lesions, 35% had an altered mental state at discharge compared to only 13% of patients with lesions in other sites, and only 50% were discharged home compared to 77% of patients with lesions in other sites. CT scan features that correlated significantly with a poor outcome following acute stroke were large lesion size, intracerebral haemorrhage, mass effect and deep white matter lesions.

    KW - Cerebral Hemorrhage/diagnostic imaging

    KW - Cerebral Infarction/diagnostic imaging

    KW - Cerebrovascular Disorders/diagnostic imaging

    KW - Follow-Up Studies

    KW - Humans

    KW - Intracranial Embolism and Thrombosis/diagnostic imaging

    KW - Tomography, X-Ray Computed

    M3 - Article

    VL - 23

    SP - 71

    EP - 74

    JO - Clinical and experimental neurology

    JF - Clinical and experimental neurology

    SN - 0196-6383

    ER -