COVID-19: A novel zoonotic disease caused by a coronavirus from China: What we know and what we don't

John S. MacKenzie, David W. Smith

Research output: Contribution to journalArticlepeer-review

289 Citations (Scopus)

Abstract

At the end of December, 2019, a new disease of unknown aetiology appeared in Wuhan, China. It was quickly identified as anovelbetacoronavirus, and related toSARS-CoVand a number of other bat-borne SARS-like coronaviruses. The virus rapidly spread to all provinces in China, as well as a number of countries overseas, and was declared a Public HealthEmergencyof InternationalConcernby theDirectorGeneral of the World Health Organization on 30 January 2020. This paper describes the evolution of the outbreak, and the known properties of the novel virus, SARS-CoV-2 and the clinical disease it causes, COVID-19, and comments on some of the important gaps in our knowledge of the virus and the disease it causes. The virus is the third zoonotic coronavirus, after SARS-CoV and MERS-CoV, but appears to be the only one with pandemic potential.

Original languageEnglish
Pages (from-to)45-50
Number of pages6
JournalMicrobiology Australia
Volume41
Issue number1
DOIs
Publication statusPublished - Mar 2020

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