[Truncated] Colorectal cancer (CRC) is the most common registrable cancer, with 11,289 new cases reported in Australia in 1998. It is the second greatest cause of cancer mortality in Australia, with 4,634 deaths occurring in that year (AIHW & AACR 2001, p48). There is considerable evidence that most, if not all, CRCs originate from benign epithelial tumours known as adenomas. The period of time that an adenoma resides within the colon or rectum is referred to as the 'dwell time'. The dwell time of adenomas is uncertain; however, evidence suggests in the region often years (Rex et al. 1996; Hoff et al. 1996). Detection and subsequent removal of adenomas during this period will disrupt the adenoma cancer sequelae and prevent a cancer developing from this site. While CRC screening is accepted as standard practice for those at high-risk, there is much debate about the public health value of screening for CRC in average-risk, asymptomatic Australians.
|Publication status||Unpublished - 2002|