Abstract
Original language | English |
---|---|
Pages (from-to) | 477-478 |
Number of pages | 2 |
Journal | Nature |
Volume | 259 |
Issue number | 5543 |
DOIs | |
Publication status | Published - 1976 |
Fingerprint
Cite this
}
Correspondence between sharp tuning and two-tone inhibition in primary auditory neurones. / Robertson, Donald.
In: Nature, Vol. 259, No. 5543, 1976, p. 477-478.Research output: Contribution to journal › Article
TY - JOUR
T1 - Correspondence between sharp tuning and two-tone inhibition in primary auditory neurones
AU - Robertson, Donald
PY - 1976
Y1 - 1976
N2 - THE sharp frequency selectivity of single primary auditory neurones in mammals contrasts with the poor mechanical tuning of the basilar membrane 1,2. This discrepancy has generally been explained by postulating some filter mechanism interposed between the basilar membrane and the excitation of auditory afferents2-4. A further property of these neurones which probably cannot be explained by basilar membrane behaviour alone is two-tone inhibition whereby the simultaneous presentation of a second tone reduces the response of a neurone to a first tone at the best, or characteristic frequency5-8. It has been suggested that this inhibition may also be a property of the additional cochlear mechanisms which follow the basilar membrane9. I now present evidence that the loss of sharp frequency selectivity of primary neurones is intimately linked to changes in two-tone inhibition and that the two phenomena might be related to a common mechanism which is vulnerable to perilymph removal. © 1975 Nature Publishing Group.
AB - THE sharp frequency selectivity of single primary auditory neurones in mammals contrasts with the poor mechanical tuning of the basilar membrane 1,2. This discrepancy has generally been explained by postulating some filter mechanism interposed between the basilar membrane and the excitation of auditory afferents2-4. A further property of these neurones which probably cannot be explained by basilar membrane behaviour alone is two-tone inhibition whereby the simultaneous presentation of a second tone reduces the response of a neurone to a first tone at the best, or characteristic frequency5-8. It has been suggested that this inhibition may also be a property of the additional cochlear mechanisms which follow the basilar membrane9. I now present evidence that the loss of sharp frequency selectivity of primary neurones is intimately linked to changes in two-tone inhibition and that the two phenomena might be related to a common mechanism which is vulnerable to perilymph removal. © 1975 Nature Publishing Group.
KW - acoustic nerve fiber guinea pig nerve cell membrane potential theoretical study tone Acoustic Stimulation Action Potentials Animal Auditory Pathways Cochlea Cochlear Nerve Guinea Pigs
U2 - 10.1038/259477a0
DO - 10.1038/259477a0
M3 - Article
VL - 259
SP - 477
EP - 478
JO - Nature
JF - Nature
SN - 0028-0836
IS - 5543
ER -