Coronavirus disease 2019 (COVID-19): A literature review

Harapan Harapan, Naoya Itoh, Amanda Yufika, Wira Winardi, Synat Keam, Haypheng Te, Dewi Megawati, Zinatul Hayati, Abram L. Wagner, Mudatsir Mudatsir

Research output: Contribution to journalReview articlepeer-review

919 Citations (Scopus)


In early December 2019, an outbreak of coronavirus disease 2019 (COVID-19), caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), occurred in Wuhan City, Hubei Province, China. On January 30, 2020 the World Health Organization declared the outbreak as a Public Health Emergency of International Concern. As of February 14, 2020, 49,053 laboratory-confirmed and 1,381 deaths have been reported globally. Perceived risk of acquiring disease has led many governments to institute a variety of control measures. We conducted a literature review of publicly available information to summarize knowledge about the pathogen and the current epidemic. In this literature review, the causative agent, pathogenesis and immune responses, epidemiology, diagnosis, treatment and management of the disease, control and preventions strategies are all reviewed.

Original languageEnglish
Pages (from-to)667-673
Number of pages7
JournalJournal of Infection and Public Health
Issue number5
Publication statusPublished - May 2020


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