Copy number variation and disease resistance in plants

Aria Dolatabadian, Dhwani Apurva Patel, David Edwards, Jacqueline Batley

Research output: Contribution to journalArticle

16 Citations (Scopus)
597 Downloads (Pure)

Abstract

Plant genome diversity varies from single nucleotide polymorphisms to large-scale deletions, insertions, duplications, or re-arrangements. These re-arrangements of sequences resulting from duplication, gains or losses of DNA segments are termed copy number variations (CNVs). During the last decade, numerous studies have emphasized the importance of CNVs as a factor affecting human phenotype; in particular, CNVs have been associated with risks for several severe diseases. In plants, the exploration of the extent and role of CNVs in resistance against pathogens and pests is just beginning. Since CNVs are likely to be associated with disease resistance in plants, an understanding of the distribution of CNVs could assist in the identification of novel plant disease-resistance genes. In this paper, we review existing information about CNVs; their importance, role and function, as well as their association with disease resistance in plants.

Original languageEnglish
Pages (from-to)2479-2490
Number of pages12
JournalTheoretical and Applied Genetics
Volume130
Issue number12
DOIs
Publication statusPublished - Dec 2017

Fingerprint Dive into the research topics of 'Copy number variation and disease resistance in plants'. Together they form a unique fingerprint.

Cite this