© 2015 Elsevier Ltd. All rights reserved. A new and practical process for the synthesis of N-arylpyridin-2-amine derivatives has been developed. Under the assistance of copper, the desired products were produced from commercially available 2-aminopyridine and aryl boronic acids in moderate to good yields with good functional group tolerance.
Chen, J., Natte, K., Man, N., Stewart, S., & Wu, X. F. (2015). Convenient copper-mediated Chan-Lam coupling of 2-aminopyridine: Facile synthesis of N-arylpyridin-2-amines. Tetrahedron Letters, 56(33), 4843-4847. https://doi.org/10.1016/j.tetlet.2015.06.092