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Contrast enhancement in Lhermitte-Duclos disease of the cerebellum: correlation of imaging with neuropathology in two cases

  • L. Spaargaren
  • , P. Cras
  • , M. A.M. Bomhof
  • , S. T. Lie
  • , A. M. de Barsy
  • , P. H. Croese
  • , J. L.J.M. Teepen
  • , V. H.J.M. Duwel
  • , J. W. Van Goethem
  • , O. Ozsarlak
  • , L. van den Hauwe
  • , A. M. De Schepper
  • , P. M. Parizel

Research output: Contribution to journalArticlepeer-review

Abstract

Lhermitte-Duclos disease (LDD), also known as dysplastic gangliocytoma, is a rare cerebellar lesion. It has long been regarded as avascular. We report two patients with surgically proven LDD in whom contrast enhancement was observed on MRI. Neuropathological examination revealed proliferation of veins. We suggest that peripheral enhancement of LDD probably reflects vascular proliferation of the cerebellar venous draining system, and should be considered part of the imaging features of LDD.

Original languageEnglish
Pages (from-to)381-385
Number of pages5
JournalNeuroradiology
Volume45
Issue number6
DOIs
Publication statusPublished - Jun 2003
Externally publishedYes

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