Concentrations of activin A, inhibin A and follistatin in human amnion, choriodecidual and placental tissues at term and preterm

Jeffrey Keelan, KW Marvin, TA Sato, LME Mccowan, M Coleman, LW Evans, NP Groome, MD Mitchell

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    Abstract

    To investigate labour-associated changes in production of activin and related hormones by gestational tissues we prepared extracts from amnion, choriodecidual and placental tissues delivered at term before labour (TNL; n=15), at term after spontaneous labour (TSL; n=15) or preterm (PTD; n=31) and measured concentrations of inhibin A, activin A and follistatin by ELISA. Activin concentrations in placental tissues were significantly (Mann-Whitney U-test; P
    Original languageEnglish
    Pages (from-to)99-106
    JournalJournal of Endocrinology
    Volume163
    DOIs
    Publication statusPublished - 1999

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