TY - JOUR
T1 - Concentration-dependent effects of N1, N11-diethylnorspermine on melanoma cell proliferation
AU - Minchin, R.F.
AU - Knight, S.
AU - Arulpragasam, Ajanthy
AU - Fogel-Petrovic, Mirjana
PY - 2006
Y1 - 2006
N2 - N-1, N-11-Diethylnorspermine (DENSPM) is a polyamine analog that is currently under investigation as a novel anticancer drug. Although it has shown promising preclinical activity, there has been large variation in responsiveness reported between different human cancers. During our studies into the causes of this variation, we observed a consistent increase in cell proliferation at low drug concentrations (
AB - N-1, N-11-Diethylnorspermine (DENSPM) is a polyamine analog that is currently under investigation as a novel anticancer drug. Although it has shown promising preclinical activity, there has been large variation in responsiveness reported between different human cancers. During our studies into the causes of this variation, we observed a consistent increase in cell proliferation at low drug concentrations (
U2 - 10.1002/ijc.21359
DO - 10.1002/ijc.21359
M3 - Article
SN - 0020-7136
VL - 118
SP - 509
EP - 512
JO - International Journal of Cancer
JF - International Journal of Cancer
ER -
