Complete remission of stage IV erythrodermic mycosis fungoides with large cell transformation through combination of pralatrexate and romidepsin followed by allogeneic hematopoietic stem cell transplantation

Aaron J. Frederiks; Katherine J. Creeper; Dominic V. Spagnolo; Paul Cannell; Dejan Radeski

doi:10.1111/ajd.13606

Complete remission of stage IV erythrodermic mycosis fungoides with large cell transformation through combination of pralatrexate and romidepsin followed by allogeneic hematopoietic stem cell transplantation

Aaron J. Frederiks, Katherine J. Creeper, Dominic V. Spagnolo, Paul Cannell, Dejan Radeski

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

We report the case of a 59-year-old woman with stage IV erythrodermic mycosis fungoides (MF) and large cell transformation who, despite failing multiple previous treatments, achieved complete remission through a combination of pralatrexate and romidepsin followed by allogeneic hematopoietic stem cell transplantation (alloSCT). Further studies are needed in focussing on this combined regimen in treating cutaneous T-cell lymphoma (CTCL) and its efficacy as a bridging regimen in facilitating successful alloSCT.

Original language	English
Pages (from-to)	e400-e403
Journal	Australasian Journal of Dermatology
Volume	62
Issue number	3
Early online date	2021
DOIs	https://doi.org/10.1111/ajd.13606
Publication status	Published - Aug 2021

Access to Document

10.1111/ajd.13606

Fingerprint

Dive into the research topics of 'Complete remission of stage IV erythrodermic mycosis fungoides with large cell transformation through combination of pralatrexate and romidepsin followed by allogeneic hematopoietic stem cell transplantation'. Together they form a unique fingerprint.

Cite this

Frederiks, A. J., Creeper, K. J., Spagnolo, D. V., Cannell, P., & Radeski, D. (2021). Complete remission of stage IV erythrodermic mycosis fungoides with large cell transformation through combination of pralatrexate and romidepsin followed by allogeneic hematopoietic stem cell transplantation. Australasian Journal of Dermatology, 62(3), e400-e403. https://doi.org/10.1111/ajd.13606

@article{317361df03954da09085ce1dd7545464,

title = "Complete remission of stage IV erythrodermic mycosis fungoides with large cell transformation through combination of pralatrexate and romidepsin followed by allogeneic hematopoietic stem cell transplantation",

abstract = "We report the case of a 59-year-old woman with stage IV erythrodermic mycosis fungoides (MF) and large cell transformation who, despite failing multiple previous treatments, achieved complete remission through a combination of pralatrexate and romidepsin followed by allogeneic hematopoietic stem cell transplantation (alloSCT). Further studies are needed in focussing on this combined regimen in treating cutaneous T-cell lymphoma (CTCL) and its efficacy as a bridging regimen in facilitating successful alloSCT.",

keywords = "allogeneic hematopoietic stem cell transplantation, large cell transformation, mycosis fungoides, pralatrexate, romidepsin",

author = "Frederiks, {Aaron J.} and Creeper, {Katherine J.} and Spagnolo, {Dominic V.} and Paul Cannell and Dejan Radeski",

year = "2021",

month = aug,

doi = "10.1111/ajd.13606",

language = "English",

volume = "62",

pages = "e400--e403",

journal = "Australasian Journal of Dermatology",

issn = "0004-8380",

publisher = "John Wiley & Sons",

number = "3",

}

Frederiks, AJ, Creeper, KJ, Spagnolo, DV, Cannell, P & Radeski, D 2021, 'Complete remission of stage IV erythrodermic mycosis fungoides with large cell transformation through combination of pralatrexate and romidepsin followed by allogeneic hematopoietic stem cell transplantation', Australasian Journal of Dermatology, vol. 62, no. 3, pp. e400-e403. https://doi.org/10.1111/ajd.13606

Complete remission of stage IV erythrodermic mycosis fungoides with large cell transformation through combination of pralatrexate and romidepsin followed by allogeneic hematopoietic stem cell transplantation. / Frederiks, Aaron J.; Creeper, Katherine J.; Spagnolo, Dominic V. et al.
In: Australasian Journal of Dermatology, Vol. 62, No. 3, 08.2021, p. e400-e403.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Complete remission of stage IV erythrodermic mycosis fungoides with large cell transformation through combination of pralatrexate and romidepsin followed by allogeneic hematopoietic stem cell transplantation

AU - Frederiks, Aaron J.

AU - Creeper, Katherine J.

AU - Spagnolo, Dominic V.

AU - Cannell, Paul

AU - Radeski, Dejan

PY - 2021/8

Y1 - 2021/8

N2 - We report the case of a 59-year-old woman with stage IV erythrodermic mycosis fungoides (MF) and large cell transformation who, despite failing multiple previous treatments, achieved complete remission through a combination of pralatrexate and romidepsin followed by allogeneic hematopoietic stem cell transplantation (alloSCT). Further studies are needed in focussing on this combined regimen in treating cutaneous T-cell lymphoma (CTCL) and its efficacy as a bridging regimen in facilitating successful alloSCT.

AB - We report the case of a 59-year-old woman with stage IV erythrodermic mycosis fungoides (MF) and large cell transformation who, despite failing multiple previous treatments, achieved complete remission through a combination of pralatrexate and romidepsin followed by allogeneic hematopoietic stem cell transplantation (alloSCT). Further studies are needed in focussing on this combined regimen in treating cutaneous T-cell lymphoma (CTCL) and its efficacy as a bridging regimen in facilitating successful alloSCT.

KW - allogeneic hematopoietic stem cell transplantation

KW - large cell transformation

KW - mycosis fungoides

KW - pralatrexate

KW - romidepsin

UR - http://www.scopus.com/inward/record.url?scp=85106322715&partnerID=8YFLogxK

U2 - 10.1111/ajd.13606

DO - 10.1111/ajd.13606

M3 - Article

C2 - 34028795

AN - SCOPUS:85106322715

SN - 0004-8380

VL - 62

SP - e400-e403

JO - Australasian Journal of Dermatology

JF - Australasian Journal of Dermatology

IS - 3

ER -

Complete remission of stage IV erythrodermic mycosis fungoides with large cell transformation through combination of pralatrexate and romidepsin followed by allogeneic hematopoietic stem cell transplantation

Abstract

Access to Document

Other files and links

Fingerprint

Cite this