Comparison of reflectivity maps and outer retinal topography in retinal disease by 3-D Fourier domain optical coherence tomography

Maciej Wojtkowski; Bartosz L. Sikorski; Iwona Gorczynska; Michalina Gora; Maciej Szkulmowski; Danuta Bukowska; Jakub Kałuzny; James G. Fujimoto; Andrzej Kowalczyk

doi:10.1364/OE.17.004189

Comparison of reflectivity maps and outer retinal topography in retinal disease by 3-D Fourier domain optical coherence tomography

Maciej Wojtkowski, Bartosz L. Sikorski, Iwona Gorczynska, Michalina Gora, Maciej Szkulmowski, Danuta Bukowska, Jakub Kałuzny, James G. Fujimoto, Andrzej Kowalczyk

Research output: Contribution to journal › Article › peer-review

34 Citations (Scopus)

Abstract

We demonstrate and compare two image processing methods for visualization and analysis of three-dimensional optical coherence tomography (OCT) data acquired in eyes with different retinal pathologies. A method of retinal layer segmentation based on a multiple intensity thresholding algorithm was implemented in order to generate simultaneously outer retinal topography maps and reflectivity maps. We compare the applicability of the two methods to the diagnosis of retinal diseases and their progression. The data presented in this contribution were acquired with a high speed (25,000 A-scans/s), high resolution (4.5 μm) spectral OCT prototype instrument operating in the ophthalmology clinic.

Original language	English
Pages (from-to)	4189-4207
Number of pages	19
Journal	Optics Express
Volume	17
Issue number	5
DOIs	https://doi.org/10.1364/OE.17.004189
Publication status	Published - 2 Mar 2009
Externally published	Yes

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abstract = "We demonstrate and compare two image processing methods for visualization and analysis of three-dimensional optical coherence tomography (OCT) data acquired in eyes with different retinal pathologies. A method of retinal layer segmentation based on a multiple intensity thresholding algorithm was implemented in order to generate simultaneously outer retinal topography maps and reflectivity maps. We compare the applicability of the two methods to the diagnosis of retinal diseases and their progression. The data presented in this contribution were acquired with a high speed (25,000 A-scans/s), high resolution (4.5 μm) spectral OCT prototype instrument operating in the ophthalmology clinic.",

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AU - Wojtkowski, Maciej

AU - Sikorski, Bartosz L.

AU - Gorczynska, Iwona

AU - Gora, Michalina

AU - Szkulmowski, Maciej

AU - Bukowska, Danuta

AU - Kałuzny, Jakub

AU - Fujimoto, James G.

AU - Kowalczyk, Andrzej

PY - 2009/3/2

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AB - We demonstrate and compare two image processing methods for visualization and analysis of three-dimensional optical coherence tomography (OCT) data acquired in eyes with different retinal pathologies. A method of retinal layer segmentation based on a multiple intensity thresholding algorithm was implemented in order to generate simultaneously outer retinal topography maps and reflectivity maps. We compare the applicability of the two methods to the diagnosis of retinal diseases and their progression. The data presented in this contribution were acquired with a high speed (25,000 A-scans/s), high resolution (4.5 μm) spectral OCT prototype instrument operating in the ophthalmology clinic.

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Comparison of reflectivity maps and outer retinal topography in retinal disease by 3-D Fourier domain optical coherence tomography

Abstract

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