Comparative epidemiology of suspected perioperative hypersensitivity reactions

Paul Michel Mertes, Didier G. Ebo, Tomaz Garcez, Michael Rose, Vito Sabato, Tomonori Takazawa, Peter J. Cooke, Russell C. Clarke, Pascale Dewachter, Lene H. Garvey, Anne B. Guttormsen, David L. Hepner, Phil M. Hopkins, David A. Khan, Helen Kolawole, Peter Kopac, Mogens Krøigaard, Jose J. Laguna, Stuart D. Marshall, Peter R. PlattPaul H.M. Sadleir, Louise C. Savic, Sinisa Savic, Gerald W. Volcheck, Susanna Voltolini

Research output: Contribution to journalReview articlepeer-review

90 Citations (Scopus)


Suspected perioperative hypersensitivity reactions are rare but contribute significantly to the morbidity and mortality of surgical procedures. Recent publications have highlighted the differences between countries concerning the respective risk of different drugs, and changes in patterns of causal agents and the emergence of new allergens. This review summarises recent information on the epidemiology of perioperative hypersensitivity reactions, with specific consideration of differences between geographic areas for the most frequently involved offending agents.

Original languageEnglish
Pages (from-to)e16-e28
JournalBritish Journal of Anaesthesia
Issue number1
Publication statusPublished - 1 Jul 2019


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