Collett's snake (Pseudechis colletti) envenoming in snake handlers

G.K. Isbister, M.R. Hooper, R. Dowsett, G. Maw, Lindsay Murray, J. White

    Research output: Contribution to journalArticle

    20 Citations (Scopus)

    Abstract

    Background: Collett's snake (Pseudechis colletti) is a member of the black snake genus and occurs in a warm temperate to sub-tropical region of central Queensland, Australia. There are no reports of bites occurring in the wild, and bites were previously thought to cause only minor effects. They are a popular snake among zoos and exotic snake keepers.Aim: To investigate the clinical effects of severe envenoming by Collett's snake, and possible treatment options.Design: Case series.Methods: Clinical and laboratory features are described for six bites, all in snake handlers.Results: All six bites were from captive snakes, resulting in severe envenoming in four. Two patients were treated early with black snake antivenom, and only developed an anticoagulant coagulopathy and mild myolysis. Two developed anticoagulant coagulopathy and severe rhabdomyolysis associated with acute renal failure, requiring haemodialysis; both received antivenom > 10 h after the bite, and initially received minimal fluid replacement. Other effects included thrombocytopenia, non-immune haemolytic anaemia and a marked leukocytosis.Discussion: Collett's snake envenoming is characterized by early generalized systemic effects (nausea, vomiting, abdominal pain, diarrhoea and headache) and an anticoagulant coagulopathy, followed in some cases by rhabdomyolysis and acute renal failure in untreated patients within 24 h. Early initiation of fluid therapy and treatment with black snake antivenom should be undertaken in all envenomed patients.
    Original languageEnglish
    Pages (from-to)109-115
    JournalQJM: an international journal of medicine
    Volume99
    Issue number2
    DOIs
    Publication statusPublished - 2006

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    Snakes
    Bites and Stings
    Antivenins
    Anticoagulants
    Rhabdomyolysis
    Acute Kidney Injury
    Queensland
    Idiopathic Thrombocytopenic Purpura
    Fluid Therapy
    Hemolytic Anemia
    Leukocytosis
    Nausea
    Abdominal Pain
    Vomiting
    Headache
    Renal Dialysis
    Diarrhea

    Cite this

    Isbister, G. K., Hooper, M. R., Dowsett, R., Maw, G., Murray, L., & White, J. (2006). Collett's snake (Pseudechis colletti) envenoming in snake handlers. QJM: an international journal of medicine, 99(2), 109-115. https://doi.org/10.1093/qjmed/hcl007
    Isbister, G.K. ; Hooper, M.R. ; Dowsett, R. ; Maw, G. ; Murray, Lindsay ; White, J. / Collett's snake (Pseudechis colletti) envenoming in snake handlers. In: QJM: an international journal of medicine. 2006 ; Vol. 99, No. 2. pp. 109-115.
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    abstract = "Background: Collett's snake (Pseudechis colletti) is a member of the black snake genus and occurs in a warm temperate to sub-tropical region of central Queensland, Australia. There are no reports of bites occurring in the wild, and bites were previously thought to cause only minor effects. They are a popular snake among zoos and exotic snake keepers.Aim: To investigate the clinical effects of severe envenoming by Collett's snake, and possible treatment options.Design: Case series.Methods: Clinical and laboratory features are described for six bites, all in snake handlers.Results: All six bites were from captive snakes, resulting in severe envenoming in four. Two patients were treated early with black snake antivenom, and only developed an anticoagulant coagulopathy and mild myolysis. Two developed anticoagulant coagulopathy and severe rhabdomyolysis associated with acute renal failure, requiring haemodialysis; both received antivenom > 10 h after the bite, and initially received minimal fluid replacement. Other effects included thrombocytopenia, non-immune haemolytic anaemia and a marked leukocytosis.Discussion: Collett's snake envenoming is characterized by early generalized systemic effects (nausea, vomiting, abdominal pain, diarrhoea and headache) and an anticoagulant coagulopathy, followed in some cases by rhabdomyolysis and acute renal failure in untreated patients within 24 h. Early initiation of fluid therapy and treatment with black snake antivenom should be undertaken in all envenomed patients.",
    author = "G.K. Isbister and M.R. Hooper and R. Dowsett and G. Maw and Lindsay Murray and J. White",
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    Isbister, GK, Hooper, MR, Dowsett, R, Maw, G, Murray, L & White, J 2006, 'Collett's snake (Pseudechis colletti) envenoming in snake handlers' QJM: an international journal of medicine, vol. 99, no. 2, pp. 109-115. https://doi.org/10.1093/qjmed/hcl007

    Collett's snake (Pseudechis colletti) envenoming in snake handlers. / Isbister, G.K.; Hooper, M.R.; Dowsett, R.; Maw, G.; Murray, Lindsay; White, J.

    In: QJM: an international journal of medicine, Vol. 99, No. 2, 2006, p. 109-115.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Collett's snake (Pseudechis colletti) envenoming in snake handlers

    AU - Isbister, G.K.

    AU - Hooper, M.R.

    AU - Dowsett, R.

    AU - Maw, G.

    AU - Murray, Lindsay

    AU - White, J.

    PY - 2006

    Y1 - 2006

    N2 - Background: Collett's snake (Pseudechis colletti) is a member of the black snake genus and occurs in a warm temperate to sub-tropical region of central Queensland, Australia. There are no reports of bites occurring in the wild, and bites were previously thought to cause only minor effects. They are a popular snake among zoos and exotic snake keepers.Aim: To investigate the clinical effects of severe envenoming by Collett's snake, and possible treatment options.Design: Case series.Methods: Clinical and laboratory features are described for six bites, all in snake handlers.Results: All six bites were from captive snakes, resulting in severe envenoming in four. Two patients were treated early with black snake antivenom, and only developed an anticoagulant coagulopathy and mild myolysis. Two developed anticoagulant coagulopathy and severe rhabdomyolysis associated with acute renal failure, requiring haemodialysis; both received antivenom > 10 h after the bite, and initially received minimal fluid replacement. Other effects included thrombocytopenia, non-immune haemolytic anaemia and a marked leukocytosis.Discussion: Collett's snake envenoming is characterized by early generalized systemic effects (nausea, vomiting, abdominal pain, diarrhoea and headache) and an anticoagulant coagulopathy, followed in some cases by rhabdomyolysis and acute renal failure in untreated patients within 24 h. Early initiation of fluid therapy and treatment with black snake antivenom should be undertaken in all envenomed patients.

    AB - Background: Collett's snake (Pseudechis colletti) is a member of the black snake genus and occurs in a warm temperate to sub-tropical region of central Queensland, Australia. There are no reports of bites occurring in the wild, and bites were previously thought to cause only minor effects. They are a popular snake among zoos and exotic snake keepers.Aim: To investigate the clinical effects of severe envenoming by Collett's snake, and possible treatment options.Design: Case series.Methods: Clinical and laboratory features are described for six bites, all in snake handlers.Results: All six bites were from captive snakes, resulting in severe envenoming in four. Two patients were treated early with black snake antivenom, and only developed an anticoagulant coagulopathy and mild myolysis. Two developed anticoagulant coagulopathy and severe rhabdomyolysis associated with acute renal failure, requiring haemodialysis; both received antivenom > 10 h after the bite, and initially received minimal fluid replacement. Other effects included thrombocytopenia, non-immune haemolytic anaemia and a marked leukocytosis.Discussion: Collett's snake envenoming is characterized by early generalized systemic effects (nausea, vomiting, abdominal pain, diarrhoea and headache) and an anticoagulant coagulopathy, followed in some cases by rhabdomyolysis and acute renal failure in untreated patients within 24 h. Early initiation of fluid therapy and treatment with black snake antivenom should be undertaken in all envenomed patients.

    U2 - 10.1093/qjmed/hcl007

    DO - 10.1093/qjmed/hcl007

    M3 - Article

    VL - 99

    SP - 109

    EP - 115

    JO - Q J M : an international journal of medicine

    JF - Q J M : an international journal of medicine

    SN - 1460-2393

    IS - 2

    ER -