Collagen and Muscle Fibrous Tissue as a Contrast Mechanism in the THz region

Shuting Fan; Zhengfang Qian; Vincent P. Wallace

doi:10.1109/IRMMW-THz.2018.8509855

Collagen and Muscle Fibrous Tissue as a Contrast Mechanism in the THz region

Shuting Fan
, Zhengfang Qian
, Vincent P. Wallace

School of Physics, Mathematics and Computing

Research output: Chapter in Book/Conference paper › Conference paper › peer-review

4 Citations (Scopus)

Abstract

We imaged a thin paraffin embedded sample with a terahertz time domain spectroscopy (THz-TDS) system. The sample was prepared from the laboratory Guinea pigs after 7 weeks recovery from a brain surgery. The surgical wound and the surrounding normal skin tissue showed a clear contrast in the terahertz band despite of the sub-wavelength thickness of the sample. The comparison between the terahertz images and the stained histological images suggests that the contrast comes from the collagen-rich wound and the muscle fibrous tissue. This work demonstrates a potential contrast mechanism in terahertz tissue imaging.

Original language	English
Title of host publication	2018 43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018
Publisher	IEEE, Institute of Electrical and Electronics Engineers
Volume	2018-September
ISBN (Electronic)	9781538638095
DOIs	https://doi.org/10.1109/IRMMW-THz.2018.8509855
Publication status	Published - 25 Oct 2018
Event	43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018 - Nagoya, Japan Duration: 9 Sept 2018 → 14 Sept 2018

Conference

Conference	43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018
Country/Territory	Japan
City	Nagoya
Period	9/09/18 → 14/09/18

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10.1109/IRMMW-THz.2018.8509855

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title = "Collagen and Muscle Fibrous Tissue as a Contrast Mechanism in the THz region",

abstract = "We imaged a thin paraffin embedded sample with a terahertz time domain spectroscopy (THz-TDS) system. The sample was prepared from the laboratory Guinea pigs after 7 weeks recovery from a brain surgery. The surgical wound and the surrounding normal skin tissue showed a clear contrast in the terahertz band despite of the sub-wavelength thickness of the sample. The comparison between the terahertz images and the stained histological images suggests that the contrast comes from the collagen-rich wound and the muscle fibrous tissue. This work demonstrates a potential contrast mechanism in terahertz tissue imaging.",

author = "Shuting Fan and Zhengfang Qian and Wallace, \{Vincent P.\}",

year = "2018",

month = oct,

day = "25",

doi = "10.1109/IRMMW-THz.2018.8509855",

language = "English",

volume = "2018-September",

booktitle = "2018 43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018",

publisher = "IEEE, Institute of Electrical and Electronics Engineers",

address = "United States",

note = "43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018 ; Conference date: 09-09-2018 Through 14-09-2018",

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Fan, S, Qian, Z & Wallace, VP 2018, Collagen and Muscle Fibrous Tissue as a Contrast Mechanism in the THz region. in 2018 43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018. vol. 2018-September, 8509855, IEEE, Institute of Electrical and Electronics Engineers, 43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018, Nagoya, Japan, 9/09/18. https://doi.org/10.1109/IRMMW-THz.2018.8509855

Collagen and Muscle Fibrous Tissue as a Contrast Mechanism in the THz region. / Fan, Shuting; Qian, Zhengfang; Wallace, Vincent P.
2018 43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018. Vol. 2018-September IEEE, Institute of Electrical and Electronics Engineers, 2018. 8509855.

Research output: Chapter in Book/Conference paper › Conference paper › peer-review

TY - GEN

T1 - Collagen and Muscle Fibrous Tissue as a Contrast Mechanism in the THz region

AU - Fan, Shuting

AU - Qian, Zhengfang

AU - Wallace, Vincent P.

PY - 2018/10/25

Y1 - 2018/10/25

N2 - We imaged a thin paraffin embedded sample with a terahertz time domain spectroscopy (THz-TDS) system. The sample was prepared from the laboratory Guinea pigs after 7 weeks recovery from a brain surgery. The surgical wound and the surrounding normal skin tissue showed a clear contrast in the terahertz band despite of the sub-wavelength thickness of the sample. The comparison between the terahertz images and the stained histological images suggests that the contrast comes from the collagen-rich wound and the muscle fibrous tissue. This work demonstrates a potential contrast mechanism in terahertz tissue imaging.

AB - We imaged a thin paraffin embedded sample with a terahertz time domain spectroscopy (THz-TDS) system. The sample was prepared from the laboratory Guinea pigs after 7 weeks recovery from a brain surgery. The surgical wound and the surrounding normal skin tissue showed a clear contrast in the terahertz band despite of the sub-wavelength thickness of the sample. The comparison between the terahertz images and the stained histological images suggests that the contrast comes from the collagen-rich wound and the muscle fibrous tissue. This work demonstrates a potential contrast mechanism in terahertz tissue imaging.

UR - https://www.scopus.com/pages/publications/85056842259

U2 - 10.1109/IRMMW-THz.2018.8509855

DO - 10.1109/IRMMW-THz.2018.8509855

M3 - Conference paper

AN - SCOPUS:85056842259

VL - 2018-September

BT - 2018 43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018

PB - IEEE, Institute of Electrical and Electronics Engineers

T2 - 43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018

Y2 - 9 September 2018 through 14 September 2020

ER -

Collagen and Muscle Fibrous Tissue as a Contrast Mechanism in the THz region

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