Abstract
Thirteen of more than 4,000 single-amino-acid-replacement mutants of the Lac repressor, generated by suppression of amber nonsense mutants, were characterized as having a cold-sensitive phenotype. However, when expressed as missense mutations, none of the replacements cause cold sensitivity, implicating the suppression mechanism as being responsible for this phenotype.
| Original language | English |
|---|---|
| Pages (from-to) | 2174-2175 |
| Journal | Journal of Bacteriology |
| Volume | 189 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 2007 |