Abstract
Cognitive functioning and hippocampal volumes in older adults with Type 2 diabetes mellitus (T2DM) were examined, revealing that T2DM patients are not a cognitively homogeneous group, with -50% exhibiting impaired functioning. Hippocampal asymmetry and reduced right hippocampal volume were associated with poorer cognition cross-sectionally, with reduced right hippocampal volume predicting cognitive decline. These findings are in the opposite direction to those in normal ageing and Alzheimer's disease, where the reductions are greater in the left than right hippocampus. A sizeable proportion of older adults with T2DM have cognitive dysfunction, which is related to selective atrophy in the right hippocampus.
| Original language | English |
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| Qualification | Doctor of Philosophy |
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| Award date | 30 Dec 2017 |
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| Publication status | Unpublished - 2017 |
Access to Document
- THESIS - DOCTOR OF PHILOSOPHY - MILNE Nicole Terese - 2017
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