Cochlear nucleus inputs to olivocochlear neurones revealed by combined anterograde and retrograde labelling in the guinea pig

Donald Robertson, Ian M. Winter

    Research output: Contribution to journalArticle

    37 Citations (Scopus)

    Abstract

    Injections of the fluorescent tracer, Fast blue (FB), into cochlear nucleus complex in guinea pig produced strong anterognade labelling of ascending projections from this nucleus. When combined with retrograde labelling of olivocochlear efferent neurones by intracochlear injection of a second fluorescent tracer, Diamidino yellow (DY), the synaptic terminals formed on these cells by projections from the cochlear nucleus could be identified. The results provide direct support for the notion that many of the ipsilateral-monaural cochlear efferents identified in physiological studies correspond to the olivocochlear neurones located in brainstem nuclei contralateral to their target cochlea.

    Original languageEnglish
    Pages (from-to)47-55
    Number of pages9
    JournalBrain Research
    Volume462
    Issue number1
    DOIs
    Publication statusPublished - 11 Oct 1988

    Fingerprint

    Cochlear Nucleus
    Cochlea
    Guinea Pigs
    Efferent Neurons
    Neurons
    Injections
    Presynaptic Terminals
    Brain Stem
    diamidino compound 253-50
    diamidino yellow

    Cite this

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    abstract = "Injections of the fluorescent tracer, Fast blue (FB), into cochlear nucleus complex in guinea pig produced strong anterognade labelling of ascending projections from this nucleus. When combined with retrograde labelling of olivocochlear efferent neurones by intracochlear injection of a second fluorescent tracer, Diamidino yellow (DY), the synaptic terminals formed on these cells by projections from the cochlear nucleus could be identified. The results provide direct support for the notion that many of the ipsilateral-monaural cochlear efferents identified in physiological studies correspond to the olivocochlear neurones located in brainstem nuclei contralateral to their target cochlea.",
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    Cochlear nucleus inputs to olivocochlear neurones revealed by combined anterograde and retrograde labelling in the guinea pig. / Robertson, Donald; Winter, Ian M.

    In: Brain Research, Vol. 462, No. 1, 11.10.1988, p. 47-55.

    Research output: Contribution to journalArticle

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