Cochlear nucleus inputs to olivocochlear neurones revealed by combined anterograde and retrograde labelling in the guinea pig

Donald Robertson; Ian M. Winter

doi:10.1016/0006-8993(88)90583-5

Cochlear nucleus inputs to olivocochlear neurones revealed by combined anterograde and retrograde labelling in the guinea pig

Donald Robertson, Ian M. Winter

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Abstract

Injections of the fluorescent tracer, Fast blue (FB), into cochlear nucleus complex in guinea pig produced strong anterognade labelling of ascending projections from this nucleus. When combined with retrograde labelling of olivocochlear efferent neurones by intracochlear injection of a second fluorescent tracer, Diamidino yellow (DY), the synaptic terminals formed on these cells by projections from the cochlear nucleus could be identified. The results provide direct support for the notion that many of the ipsilateral-monaural cochlear efferents identified in physiological studies correspond to the olivocochlear neurones located in brainstem nuclei contralateral to their target cochlea.

Original language	English
Pages (from-to)	47-55
Number of pages	9
Journal	Brain Research
Volume	462
Issue number	1
DOIs	https://doi.org/10.1016/0006-8993(88)90583-5
Publication status	Published - 11 Oct 1988

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https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023720276&doi=10.1016%2f0006-8993%2888%2990583-5&partnerID=40&md5=fbc890596eff1633523b6e9169adc4fb

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title = "Cochlear nucleus inputs to olivocochlear neurones revealed by combined anterograde and retrograde labelling in the guinea pig",

abstract = "Injections of the fluorescent tracer, Fast blue (FB), into cochlear nucleus complex in guinea pig produced strong anterognade labelling of ascending projections from this nucleus. When combined with retrograde labelling of olivocochlear efferent neurones by intracochlear injection of a second fluorescent tracer, Diamidino yellow (DY), the synaptic terminals formed on these cells by projections from the cochlear nucleus could be identified. The results provide direct support for the notion that many of the ipsilateral-monaural cochlear efferents identified in physiological studies correspond to the olivocochlear neurones located in brainstem nuclei contralateral to their target cochlea.",

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AU - Robertson, Donald

AU - Winter, Ian M.

PY - 1988/10/11

Y1 - 1988/10/11

N2 - Injections of the fluorescent tracer, Fast blue (FB), into cochlear nucleus complex in guinea pig produced strong anterognade labelling of ascending projections from this nucleus. When combined with retrograde labelling of olivocochlear efferent neurones by intracochlear injection of a second fluorescent tracer, Diamidino yellow (DY), the synaptic terminals formed on these cells by projections from the cochlear nucleus could be identified. The results provide direct support for the notion that many of the ipsilateral-monaural cochlear efferents identified in physiological studies correspond to the olivocochlear neurones located in brainstem nuclei contralateral to their target cochlea.

AB - Injections of the fluorescent tracer, Fast blue (FB), into cochlear nucleus complex in guinea pig produced strong anterognade labelling of ascending projections from this nucleus. When combined with retrograde labelling of olivocochlear efferent neurones by intracochlear injection of a second fluorescent tracer, Diamidino yellow (DY), the synaptic terminals formed on these cells by projections from the cochlear nucleus could be identified. The results provide direct support for the notion that many of the ipsilateral-monaural cochlear efferents identified in physiological studies correspond to the olivocochlear neurones located in brainstem nuclei contralateral to their target cochlea.

KW - Anterograde label

KW - Cochlear nucleus

KW - Olivocochlear neuron

KW - Retrograde label

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SN - 0006-8993

VL - 462

SP - 47

EP - 55

JO - Brain Research

JF - Brain Research

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ER -

Cochlear nucleus inputs to olivocochlear neurones revealed by combined anterograde and retrograde labelling in the guinea pig

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