Cochlear neurons: Frequency selectivity altered by perilymph removal

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Removal of perilymph from the scala tympani of the guinea pig cochlea reversibly broadened the tuning curves of single spiral ganglioll cells emanating from the basilar membrane. Thus, fluid continuity along the membrane is essential for normal cochlear function, in particular for sharp neural tuning curves. These data reveal a possible source of error in some estimates of basilar membrane motion and suggest a reappraisal of current concepts of the mechanism of sharp tuning in primary auditory nerve fibers.
Original languageEnglish
Pages (from-to)153-155
Number of pages3
JournalScience
Volume186
Issue number4159
DOIs
Publication statusPublished - 1974

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Basilar Membrane
Perilymph
Cochlea
Scala Tympani
Neurons
Cochlear Nerve
Nerve Fibers
Guinea Pigs
Research Design
Membranes

Cite this

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title = "Cochlear neurons: Frequency selectivity altered by perilymph removal",
abstract = "Removal of perilymph from the scala tympani of the guinea pig cochlea reversibly broadened the tuning curves of single spiral ganglioll cells emanating from the basilar membrane. Thus, fluid continuity along the membrane is essential for normal cochlear function, in particular for sharp neural tuning curves. These data reveal a possible source of error in some estimates of basilar membrane motion and suggest a reappraisal of current concepts of the mechanism of sharp tuning in primary auditory nerve fibers.",
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author = "Donald Robertson",
year = "1974",
doi = "10.1126/science.186.4159.153",
language = "English",
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pages = "153--155",
journal = "Science",
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Cochlear neurons: Frequency selectivity altered by perilymph removal. / Robertson, Donald.

In: Science, Vol. 186, No. 4159, 1974, p. 153-155.

Research output: Contribution to journalArticle

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N2 - Removal of perilymph from the scala tympani of the guinea pig cochlea reversibly broadened the tuning curves of single spiral ganglioll cells emanating from the basilar membrane. Thus, fluid continuity along the membrane is essential for normal cochlear function, in particular for sharp neural tuning curves. These data reveal a possible source of error in some estimates of basilar membrane motion and suggest a reappraisal of current concepts of the mechanism of sharp tuning in primary auditory nerve fibers.

AB - Removal of perilymph from the scala tympani of the guinea pig cochlea reversibly broadened the tuning curves of single spiral ganglioll cells emanating from the basilar membrane. Thus, fluid continuity along the membrane is essential for normal cochlear function, in particular for sharp neural tuning curves. These data reveal a possible source of error in some estimates of basilar membrane motion and suggest a reappraisal of current concepts of the mechanism of sharp tuning in primary auditory nerve fibers.

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JF - Science

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