Clonal expansion of new penicillin-resistant clade of neisseria meningitidis serogroup w clonal complex 11, Australia

Shakeel Mowlaboccus; Keith A. Jolley; James E. Bray; Stanley Pang; Yung Thin Lee; Jane D. Bew; David J. Speers; Anthony D. Keil; Geoffrey W. Coombs; Charlene M. Kahler

doi:10.3201/eid2308.170259

Clonal expansion of new penicillin-resistant clade of neisseria meningitidis serogroup w clonal complex 11, Australia

Shakeel Mowlaboccus, Keith A. Jolley, James E. Bray, Stanley Pang, Yung Thin Lee, Jane D. Bew, David J. Speers, Anthony D. Keil, Geoffrey W. Coombs, Charlene M. Kahler

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27 Citations (Scopus)

Abstract

In Western Australia, Neisseria meningitidis serogroup W clonal complex 11 became the predominant cause of invasive meningococcal disease in 2016. We used core-genome analysis to show emergence of a penicillin-resistant clade that had the penA_253 allele. This new penicillin-resistant clade might affect treatment regimens for this disease.

Original language	English
Pages (from-to)	1364-1367
Number of pages	4
Journal	Emerging Infectious Diseases
Volume	23
Issue number	8
DOIs	https://doi.org/10.3201/eid2308.170259
Publication status	Published - 1 Aug 2017

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10.3201/eid2308.170259Licence: CC BY

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title = "Clonal expansion of new penicillin-resistant clade of neisseria meningitidis serogroup w clonal complex 11, Australia",

abstract = "In Western Australia, Neisseria meningitidis serogroup W clonal complex 11 became the predominant cause of invasive meningococcal disease in 2016. We used core-genome analysis to show emergence of a penicillin-resistant clade that had the penA_253 allele. This new penicillin-resistant clade might affect treatment regimens for this disease.",

author = "Shakeel Mowlaboccus and Jolley, {Keith A.} and Bray, {James E.} and Stanley Pang and Lee, {Yung Thin} and Bew, {Jane D.} and Speers, {David J.} and Keil, {Anthony D.} and Coombs, {Geoffrey W.} and Kahler, {Charlene M.}",

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AU - Mowlaboccus, Shakeel

AU - Jolley, Keith A.

AU - Bray, James E.

AU - Pang, Stanley

AU - Lee, Yung Thin

AU - Bew, Jane D.

AU - Speers, David J.

AU - Keil, Anthony D.

AU - Coombs, Geoffrey W.

AU - Kahler, Charlene M.

PY - 2017/8/1

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AB - In Western Australia, Neisseria meningitidis serogroup W clonal complex 11 became the predominant cause of invasive meningococcal disease in 2016. We used core-genome analysis to show emergence of a penicillin-resistant clade that had the penA_253 allele. This new penicillin-resistant clade might affect treatment regimens for this disease.

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JF - Emerging Infectious Diseases

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Clonal expansion of new penicillin-resistant clade of neisseria meningitidis serogroup w clonal complex 11, Australia

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The Role of Lipooligosaccharide Phosphoethanolamine Transferases in the Pathogenesis of Neisseria Meningitidis & N Gonorrhoeae

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Clonal expansion of new penicillin-resistant clade of neisseria meningitidis serogroup w clonal complex 11, Australia

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The Role of Lipooligosaccharide Phosphoethanolamine Transferases in the Pathogenesis of Neisseria Meningitidis & N Gonorrhoeae

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