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Abstract
Advanced hybrid closed loop (AHCL) therapy with the Medtronic MiniMedTM 780G system improves glycemia, however the clinical outcomes in younger children remain less established. This pilot study aimed to explore the CGM metrics while on AHCL in very young children. Children between two and seven years of age and on insulin pump therapy were recruited. A 2-week phase in Manual Mode was followed by a 6-week AHCL phase. CGM metrics were analyzed to review glycemic outcomes. Out of 11 participants enrolled [mean (SD) age 5.3 (0.8) years), 10 completed the study. Time in closed loop was 96.7 (3.9)%. In AHCL, participants had a mean (SD) time in range of 72.6 (7.4)% and spent 3.0 (1.74 )% and 0.63 (0.46)% in time < 70 mg/dl and < 54 mg/dl respectively. AHCL is a feasible option for management of young children with type 1 diabetes.
| Original language | English |
|---|---|
| Pages (from-to) | 341-345 |
| Number of pages | 5 |
| Journal | Diabetes Technology & Therapeutics |
| Volume | 26 |
| Issue number | 5 |
| Early online date | 30 Apr 2024 |
| DOIs | |
| Publication status | Published - 1 May 2024 |
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Dive into the research topics of 'Clinical outcomes with MiniMedTM 780G Advanced Hybrid Closed Loop Therapy in 2- to 6-year-old children with Type 1 diabetes'. Together they form a unique fingerprint.Projects
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Jones Improving the Lives of Young People with Type 1 Diabetes using State of the Art Therapies
Jones, T. (Investigator 01), Davis, E. (Investigator 02), Fournier, P. (Investigator 03), Keenan, D. (Investigator 04), Grey, M. (Investigator 05), Weinzimer, S. (Investigator 06), Geelhoed, E. (Investigator 07), Cross, D. (Investigator 08) & Tamborlane, W. (Investigator 09)
NHMRC National Health and Medical Research Council
1/01/15 → 30/04/21
Project: Research