Abstract
Currently, 20-30% of patients undergoing breast-conserving surgery require a second surgery due to tumour being found within the margin of the excised lump, determined days following surgery. The work presented in this thesis aims to develop a widefield optical coherence elastography system suitable for intraoperative margin assessment to reduce additional procedures. Early feasibility studies are presented investigating the ability for three optical coherence elastography variants to visualise a range of tumour morphologies In human breast tissue. The thesis demonstrates the clinical feasibility of optical coherence elastography for tumour margin assessment and provides a strong foundation for future clinical translation.
| Original language | English |
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| Qualification | Doctor of Philosophy |
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| Award date | 22 Aug 2019 |
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| Publication status | Unpublished - 2019 |
Access to Document
- TH19 232 THESIS - DOCTOR OF PHILOSOPHY - ALLEN Wesley Maurice - 2019
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