Characteristics and outcomes of patients presenting to the emergency department with Sepsis

Irwani Ibrahim

Research output: ThesisMaster's Thesis

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[Truncated abstract] Background Sepsis is a common and highly lethal disease. Emergency Department (ED) plays an increasingly vital role in early recognition and management. Knowledge of the epidemiology of sepsis in the ED can identify factors that can influence both short and long term outcomes. Aim The aim of this thesis is to describe the characteristics and the in-hospital and long term outcomes of patients who are diagnosed with sepsis in Western Australian hospital Emergency Departments from 2001 to 2006 inclusive. Methods The project consisted of a preliminary and a main study which were based on linked data analysis. The preliminary study was a single-centre cross sectional study conducted to determine the fields in the Emergency Department Information System (EDIS) in order to identify sepsis patient in the ED for the main study. The Royal Perth Hospital Intensive Care Unit (ICU) dataset and the EDIS dataset were used and comprised ED patients who were admitted to the ICU within 24 hours of ED discharge. These patients were then grouped into the severe sepsis and non-severe sepsis group based on their ICU diagnosis. International Classification of Diseases-10-AM (ICD-10-AM) codes in the ED diagnosis field for each patient, identified as the most suitable field to identify sepsis patients in the ED, were grouped into meaningful code-type categories and each category was compared against the corresponding ICU diagnosis to obtain the sensitivity, specificity, negative predictive value and positive predictive value (PPV). ICD-10-AM codes A41.9 which described unspecified sepsis was chosen to establish the cohort for the main study...
Original languageEnglish
Publication statusUnpublished - 2009

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