Characterisation of low-intensity repetitive transcranial magnetic stimulation induced neuroplasticity in rodent and experimental models

    Research output: ThesisDoctoral Thesis

    404 Downloads (Pure)

    Abstract

    Repetitive transcranial magnetic stimulation (rTMS) is commonly used to induce neuroplasticity in humans. However, the physiological mechanisms underlying rTMS-induced neuroplasticity remain unclear. This thesis investigates the mechanisms of low-intensity rTMS (LI-rTMS) induced plasticity in the intact and injured nervous systems using rodent and experimental models. In addition, we describe the development and validation of rodent-specific rTMS coils. Our results show that Ll-rTMS induces functional and behavioural plasticity in the intact nervous system but fails to induce neuroplasticity following neurotrauma .The outcomes of this thesis provide critical Insights into the mechanisms and use of rTMS that will inform clinical practice.
    Original languageEnglish
    QualificationDoctor of Philosophy
    Awarding Institution
    • The University of Western Australia
    Award date5 Jan 2017
    Publication statusUnpublished - 2016

    Fingerprint Dive into the research topics of 'Characterisation of low-intensity repetitive transcranial magnetic stimulation induced neuroplasticity in rodent and experimental models'. Together they form a unique fingerprint.

  • Cite this