Changes in enzyme binding and activity during aestivation in the frog Neobatrachus pelobatoides

J. Flanigan, P. Withers, Ken Storey, M. Guppy

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

1. 1. The proportion of aldolase and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) associated with the particulate fraction of a cell was measured in aestivating and non-aestivating Neobarrachus pelobatoides. 2. 2. Reduced binding of these enzymes was found in the brain, indicating lower glycolytic flux. This was not correlated to metabolic rate suggesting that glycolytic rate was reduced in this tissue in the early stages of aestivation, possibly due to a change in fuel use. 3. 3. Measurement of total enzyme levels showed that the liver of aestivating frogs had less GAPDH and less aldolase than non-aestivating frogs. © 1990.
Original languageEnglish
Pages (from-to)67-71
Number of pages5
JournalComparative Biochemistry and Physiology -- Part B: Biochemistry
Volume96
Issue number1
DOIs
Publication statusPublished - 1990

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