Cerebral microbleeds and fatigue in stroke

W. Tang, X. Liu, Y. Chen, J.M. Abrigo, W.C. Chu, V. Mok, Gabor Ungvári, K. Wong

    Research output: Contribution to journalArticle

    5 Citations (Scopus)

    Abstract

    Background and Purpose: Poststroke fatigue (PSF) is a frequent and persistent problem in stroke survivors. The neuroanatomical model of PSF remains unclear. This study examined the association between PSF and cerebral microbleeds (CMBs). Methods: The sample comprised 199 patients with acute ischemic stroke. A psychiatrist who was blind to the subjects' radiological data administered the Chinese version of the Fatigue Severity Scale. PSF was defined as a Fatigue Severity Scale score of 4.0 or more. The locations of CMBs were evaluated with magnetic resonance imaging within 7 days of admission. Results: Of the 199 patients screened, 47 (23.6%) had PSF. The PSF group had a higher Geriatric Depression Scale score (p <0.001) and a trend for a higher age (p = 0.074). The proportion of patients with deep CMBs was significantly higher in the PSF group (66.0 vs. 48.7%; p = 0.038). The presence of deep CMBs was a significant independent predictor of PSF with an odds ratio of 2.68 (p = 0.016). Conclusion: The results suggest that deep CMBs are associated with a higher risk of PSF. Further studies are needed to clarify whether CMBs affect the clinical presentation, treatment response and outcome of PSF. © 2014 S. Karger AG, Basel.
    Original languageEnglish
    Pages (from-to)213-216
    JournalEuropean Neurology
    Volume71
    Issue number5-6
    DOIs
    Publication statusPublished - 2014

    Fingerprint

    Fatigue
    Stroke
    Geriatrics
    Psychiatry
    Survivors
    Odds Ratio
    Magnetic Resonance Imaging
    Depression

    Cite this

    Tang, W., Liu, X., Chen, Y., Abrigo, J. M., Chu, W. C., Mok, V., ... Wong, K. (2014). Cerebral microbleeds and fatigue in stroke. European Neurology, 71(5-6), 213-216. https://doi.org/10.1159/000354845
    Tang, W. ; Liu, X. ; Chen, Y. ; Abrigo, J.M. ; Chu, W.C. ; Mok, V. ; Ungvári, Gabor ; Wong, K. / Cerebral microbleeds and fatigue in stroke. In: European Neurology. 2014 ; Vol. 71, No. 5-6. pp. 213-216.
    @article{4f7e265e79c44f8086d73e33a801a531,
    title = "Cerebral microbleeds and fatigue in stroke",
    abstract = "Background and Purpose: Poststroke fatigue (PSF) is a frequent and persistent problem in stroke survivors. The neuroanatomical model of PSF remains unclear. This study examined the association between PSF and cerebral microbleeds (CMBs). Methods: The sample comprised 199 patients with acute ischemic stroke. A psychiatrist who was blind to the subjects' radiological data administered the Chinese version of the Fatigue Severity Scale. PSF was defined as a Fatigue Severity Scale score of 4.0 or more. The locations of CMBs were evaluated with magnetic resonance imaging within 7 days of admission. Results: Of the 199 patients screened, 47 (23.6{\%}) had PSF. The PSF group had a higher Geriatric Depression Scale score (p <0.001) and a trend for a higher age (p = 0.074). The proportion of patients with deep CMBs was significantly higher in the PSF group (66.0 vs. 48.7{\%}; p = 0.038). The presence of deep CMBs was a significant independent predictor of PSF with an odds ratio of 2.68 (p = 0.016). Conclusion: The results suggest that deep CMBs are associated with a higher risk of PSF. Further studies are needed to clarify whether CMBs affect the clinical presentation, treatment response and outcome of PSF. {\circledC} 2014 S. Karger AG, Basel.",
    author = "W. Tang and X. Liu and Y. Chen and J.M. Abrigo and W.C. Chu and V. Mok and Gabor Ungv{\'a}ri and K. Wong",
    year = "2014",
    doi = "10.1159/000354845",
    language = "English",
    volume = "71",
    pages = "213--216",
    journal = "European Neurology",
    issn = "0014-3022",
    publisher = "S Karger AG",
    number = "5-6",

    }

    Tang, W, Liu, X, Chen, Y, Abrigo, JM, Chu, WC, Mok, V, Ungvári, G & Wong, K 2014, 'Cerebral microbleeds and fatigue in stroke' European Neurology, vol. 71, no. 5-6, pp. 213-216. https://doi.org/10.1159/000354845

    Cerebral microbleeds and fatigue in stroke. / Tang, W.; Liu, X.; Chen, Y.; Abrigo, J.M.; Chu, W.C.; Mok, V.; Ungvári, Gabor; Wong, K.

    In: European Neurology, Vol. 71, No. 5-6, 2014, p. 213-216.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Cerebral microbleeds and fatigue in stroke

    AU - Tang, W.

    AU - Liu, X.

    AU - Chen, Y.

    AU - Abrigo, J.M.

    AU - Chu, W.C.

    AU - Mok, V.

    AU - Ungvári, Gabor

    AU - Wong, K.

    PY - 2014

    Y1 - 2014

    N2 - Background and Purpose: Poststroke fatigue (PSF) is a frequent and persistent problem in stroke survivors. The neuroanatomical model of PSF remains unclear. This study examined the association between PSF and cerebral microbleeds (CMBs). Methods: The sample comprised 199 patients with acute ischemic stroke. A psychiatrist who was blind to the subjects' radiological data administered the Chinese version of the Fatigue Severity Scale. PSF was defined as a Fatigue Severity Scale score of 4.0 or more. The locations of CMBs were evaluated with magnetic resonance imaging within 7 days of admission. Results: Of the 199 patients screened, 47 (23.6%) had PSF. The PSF group had a higher Geriatric Depression Scale score (p <0.001) and a trend for a higher age (p = 0.074). The proportion of patients with deep CMBs was significantly higher in the PSF group (66.0 vs. 48.7%; p = 0.038). The presence of deep CMBs was a significant independent predictor of PSF with an odds ratio of 2.68 (p = 0.016). Conclusion: The results suggest that deep CMBs are associated with a higher risk of PSF. Further studies are needed to clarify whether CMBs affect the clinical presentation, treatment response and outcome of PSF. © 2014 S. Karger AG, Basel.

    AB - Background and Purpose: Poststroke fatigue (PSF) is a frequent and persistent problem in stroke survivors. The neuroanatomical model of PSF remains unclear. This study examined the association between PSF and cerebral microbleeds (CMBs). Methods: The sample comprised 199 patients with acute ischemic stroke. A psychiatrist who was blind to the subjects' radiological data administered the Chinese version of the Fatigue Severity Scale. PSF was defined as a Fatigue Severity Scale score of 4.0 or more. The locations of CMBs were evaluated with magnetic resonance imaging within 7 days of admission. Results: Of the 199 patients screened, 47 (23.6%) had PSF. The PSF group had a higher Geriatric Depression Scale score (p <0.001) and a trend for a higher age (p = 0.074). The proportion of patients with deep CMBs was significantly higher in the PSF group (66.0 vs. 48.7%; p = 0.038). The presence of deep CMBs was a significant independent predictor of PSF with an odds ratio of 2.68 (p = 0.016). Conclusion: The results suggest that deep CMBs are associated with a higher risk of PSF. Further studies are needed to clarify whether CMBs affect the clinical presentation, treatment response and outcome of PSF. © 2014 S. Karger AG, Basel.

    U2 - 10.1159/000354845

    DO - 10.1159/000354845

    M3 - Article

    VL - 71

    SP - 213

    EP - 216

    JO - European Neurology

    JF - European Neurology

    SN - 0014-3022

    IS - 5-6

    ER -

    Tang W, Liu X, Chen Y, Abrigo JM, Chu WC, Mok V et al. Cerebral microbleeds and fatigue in stroke. European Neurology. 2014;71(5-6):213-216. https://doi.org/10.1159/000354845