Cardiovascular consequences of hypercalcemia during activity in two species of amphibian

S.S. Hillman, P.C. Withers, W.B. Palioca, J.A. Ruben

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8 Citations (Scopus)


Exercise induced both a significant acidosis and hypercalcemia, measured as either total or ionic calcium in two species of amphibian, Bufo marinus and Rana catesbeiana. Hypercarbia induced a significant acidosis in both species but a significant hypercalcemia only in Bufo. Induction of hypercalcemia by infusion of Ca to concentrations equal to or greater than induced by exercise and hypercarbia had no significant effects in either species on mean arterial pressure, maximal rate of rise of systemic arterial pressure, blood flow rate, heart rate, pulse volume, or peripheral resistance during exercise. The ratio of ionic to total calcium was not significantly altered within a species by an experimental protocol. These data indicate that there are no discernible cardiovascular consequences during exercise of hypercalcemia induced by exercise or hypercarbia. Copyright © 1987 Wiley‐Liss, Inc., A Wiley Company
Original languageEnglish
Pages (from-to)303-308
Number of pages6
JournalJournal of Experimental Zoology
Issue number3
Publication statusPublished - 1987


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