Cardiovascular adjustments to enforced activity in the anuran amphibian, Bufo marinus

P. C. Withers, S. S. Hillman, L. A. Simmons, A. C. Zygmunt

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

1. 1. Oxygen consumption rate and cardiovascular variables contributing to O2 transport were measured for marine toads (S. marinus) at rest and during enforced activity. 2. 2. An 8.3 fold increase in VO2 with activity was accompanied by elevation of heart rate, systemic arch blood flow, and arterial and venous blood pressures. Systemic arch pulse volume declined slightly with activity. Peripheral vascular resistance declined 40% with activity. Arterial PO2 and pco2 increased with activity, whereas pH declined. Venous pco2 increased and po2 and pH declined with activity. Consequently, the arteriovenous difference in po2 increased from 12 torr at rest to 62 torr during activity: the calculated arteriovenous difference in blood % saturation increased from 6.5 to 58%. There was a metabolic acidosis during activity. 3. 3. The % contributions of the cardiovascular variables to the VO2 increment during activity were: heart rate, +17%: systemic arch pulse volume, -2%; arteriovenous % saturation difference, +85%. 4. 4. The large contribution of arteriovenous difference is due to both elevation of arterial and decline of venous saturation. © 1988.
Original languageEnglish
Pages (from-to)45-49
Number of pages5
JournalComparative Biochemistry and Physiology -- Part A: Physiology
Volume89
Issue number1
DOIs
Publication statusPublished - 1988

Fingerprint

Bufo marinus
Amphibians
Vascular Resistance
Heart Rate
Venous Pressure
Acidosis
Oxygen Consumption
Arterial Pressure

Cite this

@article{6da102de869e4837a23a7bc7200f931e,
title = "Cardiovascular adjustments to enforced activity in the anuran amphibian, Bufo marinus",
abstract = "1. 1. Oxygen consumption rate and cardiovascular variables contributing to O2 transport were measured for marine toads (S. marinus) at rest and during enforced activity. 2. 2. An 8.3 fold increase in VO2 with activity was accompanied by elevation of heart rate, systemic arch blood flow, and arterial and venous blood pressures. Systemic arch pulse volume declined slightly with activity. Peripheral vascular resistance declined 40{\%} with activity. Arterial PO2 and pco2 increased with activity, whereas pH declined. Venous pco2 increased and po2 and pH declined with activity. Consequently, the arteriovenous difference in po2 increased from 12 torr at rest to 62 torr during activity: the calculated arteriovenous difference in blood {\%} saturation increased from 6.5 to 58{\%}. There was a metabolic acidosis during activity. 3. 3. The {\%} contributions of the cardiovascular variables to the VO2 increment during activity were: heart rate, +17{\%}: systemic arch pulse volume, -2{\%}; arteriovenous {\%} saturation difference, +85{\%}. 4. 4. The large contribution of arteriovenous difference is due to both elevation of arterial and decline of venous saturation. {\circledC} 1988.",
author = "Withers, {P. C.} and Hillman, {S. S.} and Simmons, {L. A.} and Zygmunt, {A. C.}",
year = "1988",
doi = "10.1016/0300-9629(88)91136-x",
language = "English",
volume = "89",
pages = "45--49",
journal = "Comparative Biochemistry and Physiology -Part A : Molecular and Integrative Physiology",
issn = "1095-6433",
publisher = "Elsevier",
number = "1",

}

Cardiovascular adjustments to enforced activity in the anuran amphibian, Bufo marinus. / Withers, P. C.; Hillman, S. S.; Simmons, L. A.; Zygmunt, A. C.

In: Comparative Biochemistry and Physiology -- Part A: Physiology, Vol. 89, No. 1, 1988, p. 45-49.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Cardiovascular adjustments to enforced activity in the anuran amphibian, Bufo marinus

AU - Withers, P. C.

AU - Hillman, S. S.

AU - Simmons, L. A.

AU - Zygmunt, A. C.

PY - 1988

Y1 - 1988

N2 - 1. 1. Oxygen consumption rate and cardiovascular variables contributing to O2 transport were measured for marine toads (S. marinus) at rest and during enforced activity. 2. 2. An 8.3 fold increase in VO2 with activity was accompanied by elevation of heart rate, systemic arch blood flow, and arterial and venous blood pressures. Systemic arch pulse volume declined slightly with activity. Peripheral vascular resistance declined 40% with activity. Arterial PO2 and pco2 increased with activity, whereas pH declined. Venous pco2 increased and po2 and pH declined with activity. Consequently, the arteriovenous difference in po2 increased from 12 torr at rest to 62 torr during activity: the calculated arteriovenous difference in blood % saturation increased from 6.5 to 58%. There was a metabolic acidosis during activity. 3. 3. The % contributions of the cardiovascular variables to the VO2 increment during activity were: heart rate, +17%: systemic arch pulse volume, -2%; arteriovenous % saturation difference, +85%. 4. 4. The large contribution of arteriovenous difference is due to both elevation of arterial and decline of venous saturation. © 1988.

AB - 1. 1. Oxygen consumption rate and cardiovascular variables contributing to O2 transport were measured for marine toads (S. marinus) at rest and during enforced activity. 2. 2. An 8.3 fold increase in VO2 with activity was accompanied by elevation of heart rate, systemic arch blood flow, and arterial and venous blood pressures. Systemic arch pulse volume declined slightly with activity. Peripheral vascular resistance declined 40% with activity. Arterial PO2 and pco2 increased with activity, whereas pH declined. Venous pco2 increased and po2 and pH declined with activity. Consequently, the arteriovenous difference in po2 increased from 12 torr at rest to 62 torr during activity: the calculated arteriovenous difference in blood % saturation increased from 6.5 to 58%. There was a metabolic acidosis during activity. 3. 3. The % contributions of the cardiovascular variables to the VO2 increment during activity were: heart rate, +17%: systemic arch pulse volume, -2%; arteriovenous % saturation difference, +85%. 4. 4. The large contribution of arteriovenous difference is due to both elevation of arterial and decline of venous saturation. © 1988.

U2 - 10.1016/0300-9629(88)91136-x

DO - 10.1016/0300-9629(88)91136-x

M3 - Article

VL - 89

SP - 45

EP - 49

JO - Comparative Biochemistry and Physiology -Part A : Molecular and Integrative Physiology

JF - Comparative Biochemistry and Physiology -Part A : Molecular and Integrative Physiology

SN - 1095-6433

IS - 1

ER -