Cardioactive Iridoid Glycosides from Eremophila species

M. Pennacchio; Y.M. Syah; Emilio Ghisalberti; E. Alexander

doi:10.1016/S0944-7113(97)80041-4

Cardioactive Iridoid Glycosides from Eremophila species

M. Pennacchio, Y.M. Syah, Emilio Ghisalberti, E. Alexander

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Abstract

Four iridoid glycosides isolated from different species of Eremophila (Myoporaceae) were tested for their effects on the Langendorff rat heart. Melampyroside (1), verminoside (2), ferruloylajugol (3) and catalpol (4) all significantly decreased contractile force in the isolated rat heart test. Within a minute after administration all, except catalpol, significantly increased heart rate and coronary perfusion rate. These results are compared to those of other cardioactive iridoid glycosides described in the literature.

Original language	English
Pages (from-to)	325-330
Journal	Phytomedicine
Volume	4
DOIs	https://doi.org/10.1016/S0944-7113(97)80041-4
Publication status	Published - 1997

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title = "Cardioactive Iridoid Glycosides from Eremophila species",

abstract = "Four iridoid glycosides isolated from different species of Eremophila (Myoporaceae) were tested for their effects on the Langendorff rat heart. Melampyroside (1), verminoside (2), ferruloylajugol (3) and catalpol (4) all significantly decreased contractile force in the isolated rat heart test. Within a minute after administration all, except catalpol, significantly increased heart rate and coronary perfusion rate. These results are compared to those of other cardioactive iridoid glycosides described in the literature.",

author = "M. Pennacchio and Y.M. Syah and Emilio Ghisalberti and E. Alexander",

year = "1997",

doi = "10.1016/S0944-7113(97)80041-4",

language = "English",

volume = "4",

pages = "325--330",

journal = "Phytomedicine",

publisher = "Urban und Fischer Verlag Jena",

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T1 - Cardioactive Iridoid Glycosides from Eremophila species

AU - Pennacchio, M.

AU - Syah, Y.M.

AU - Ghisalberti, Emilio

AU - Alexander, E.

PY - 1997

Y1 - 1997

N2 - Four iridoid glycosides isolated from different species of Eremophila (Myoporaceae) were tested for their effects on the Langendorff rat heart. Melampyroside (1), verminoside (2), ferruloylajugol (3) and catalpol (4) all significantly decreased contractile force in the isolated rat heart test. Within a minute after administration all, except catalpol, significantly increased heart rate and coronary perfusion rate. These results are compared to those of other cardioactive iridoid glycosides described in the literature.

AB - Four iridoid glycosides isolated from different species of Eremophila (Myoporaceae) were tested for their effects on the Langendorff rat heart. Melampyroside (1), verminoside (2), ferruloylajugol (3) and catalpol (4) all significantly decreased contractile force in the isolated rat heart test. Within a minute after administration all, except catalpol, significantly increased heart rate and coronary perfusion rate. These results are compared to those of other cardioactive iridoid glycosides described in the literature.

U2 - 10.1016/S0944-7113(97)80041-4

DO - 10.1016/S0944-7113(97)80041-4

M3 - Article

VL - 4

SP - 325

EP - 330

JO - Phytomedicine

JF - Phytomedicine

ER -

Cardioactive Iridoid Glycosides from Eremophila species

Abstract

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