Cardioactive compounds from Eremophila species

M. Pennacchio, Y.M. Syah, Emilio Ghisalberti, E. Alexander

Research output: Contribution to journalArticlepeer-review

44 Citations (Scopus)

Abstract

The isolation and identification of two cardioactive compounds from two Eremophila species (Myoporaceae) considered important in the pharmacopoeia of the Australian Aboriginal people is described. Verbascoside, isolated from the methanol and water extracts of E. alternifolia leaves, mediated significant increases in chronotropism, inotropism and coronary perfusion rate (CPR) in the Langendorff rat heart. Geniposidic acid, isolated from the methanol extract of E. longifolia leaves, mediated an inhibitory effect with significant negative chronotropism, negative inotropism and CPR.
Original languageEnglish
Pages (from-to)21-27
JournalJournal of Ethnopharmacology
Volume53
DOIs
Publication statusPublished - 1996

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