Can pre-hospital administration reduce time to initial antibiotic therapy in septic patients?

on behalf of the ARISE Investigators

doi:10.1111/1742-6723.13282

Can pre-hospital administration reduce time to initial antibiotic therapy in septic patients?

on behalf of the ARISE Investigators

Emergency Medicine

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Objective: To quantify the potential time saved with pre-hospital antibiotic therapy in sepsis. Methods: Study data for adult patients transported by Ambulance Victoria (AV), and enrolled into the Australasian Resuscitation In Sepsis Evaluation (ARISE), were linked with pre-hospital electronic records. Results: An AV record was identified for 240 of 341 ARISE patients. The pre-hospital case notes referred to potential infection in 165 patients. The median time to first antibiotic administration from loading the patient into the ambulance was 107 (74–160) min. Conclusions: ARISE patients in Victoria were frequently identified pre-hospital. An opportunity exists to study the feasibility of pre-hospital antibiotic therapy.

Original language	English
Pages (from-to)	669-672
Number of pages	4
Journal	EMA - Emergency Medicine Australasia
Volume	31
Issue number	4
DOIs	https://doi.org/10.1111/1742-6723.13282
Publication status	Published - 1 Aug 2019

Access to Document

10.1111/1742-6723.13282

Cite this

@article{fbcf4b77321b42f8b909dba76e866f43,

title = "Can pre-hospital administration reduce time to initial antibiotic therapy in septic patients?",

abstract = "Objective: To quantify the potential time saved with pre-hospital antibiotic therapy in sepsis. Methods: Study data for adult patients transported by Ambulance Victoria (AV), and enrolled into the Australasian Resuscitation In Sepsis Evaluation (ARISE), were linked with pre-hospital electronic records. Results: An AV record was identified for 240 of 341 ARISE patients. The pre-hospital case notes referred to potential infection in 165 patients. The median time to first antibiotic administration from loading the patient into the ambulance was 107 (74–160) min. Conclusions: ARISE patients in Victoria were frequently identified pre-hospital. An opportunity exists to study the feasibility of pre-hospital antibiotic therapy.",

keywords = "antibiotics, out of hospital, pre-hospital, sepsis, sepsis management",

author = "{on behalf of the ARISE Investigators} and Daniel Cudini and Karen Smith and Stephen Bernard and Michael Stephenson and Emily Andrew and Peter Cameron and Mark Lum and Andrew Udy and V. Bennett and J. Board and P. McCracken and S. McGloughlin and V. Nanjayya and A. Teo and R. Bellomo and S. Bolch and G. Eastwood and F. Kerr and L. Peak and Helen Young and J. Edington and Jason Fletcher and Smith, {Julie K.} and Cross, {Anthony M.} and D. Flemming and M. Grummisch and A. Purdue and T. Coles and Howard Connor and J. Dennett and {Van Berkel}, A. and G. Braitberg and B. O'Bree and Katherine Shepherd and Sanjiv Vij and Sharon Allsop and D. Haji and K. Haji and J. Vuat and A. Bone and T. Elderkin and N. Orford and M. Ragg and Jonathan Dowling and P. Galt and T. Lamac and D. Lightfoot and Craig Walker and MacIsaac, {Christopher M.} and K. Gorman and A. Jordan and Moore, {Lucy A.} and E. Farone and Holmes, {Jennifer A.} and J. Santamaria and C. Winter and Samantha Bates and Butler, {Jenie P.} and C. French and A. Tippett",

year = "2019",

month = aug,

day = "1",

doi = "10.1111/1742-6723.13282",

language = "English",

volume = "31",

pages = "669--672",

journal = "EMA - Emergency Medicine Australasia",

issn = "1742-6731",