Butyrylcholinesterase K variant and Alzheimer's disease

P.K. Panegyres, C.D. Mamotte, S.D. Vasikaran, Steve Wilton, V. Fabian, Byron Kakulas

Research output: Contribution to journalArticlepeer-review

26 Citations (Scopus)

Abstract

This study attempted to corroborate findings on the association between butyrylcholinesterase K variant and Alzheimer's disease. This was performed on an autopsy-confirmed series of patients with Alzheimer's disease and controls. The butyrylcholinesterase K variant was found to be of increased allele frequency in patients with sporadic Alzheimer's disease. When related to APOE epsilon 4 typing the association was specific but not sensitive for the diagnosis of Alzheimer's disease.
Original languageEnglish
Pages (from-to)369-370
JournalJournal of Neurology
Volume246
DOIs
Publication statusPublished - 1999

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