Burn injury and long-term nervous system morbidity: A population-based cohort study

Objective: To investigate if children and adults who are hospitalised for a burn injury have increased longterm hospital use for nervous system diseases. Design: A population-based retrospective cohort study using linked administrative health data from the Western Australian Data Linkage System. Participants: Records of 30 997 persons hospitalised for a first burn injury in Western Australia during the period 1980.2012, and 123 399 persons who were age and gender frequency matched with no injury admissions randomly selected from Western Australiafs birth registrations and electoral roll. Main outcome measures: Admission rates and summed length of stay for nervous system diseases. Negative binomial and Cox proportional hazards regression modelling were used to generate incidence rate ratios (IRRs) and HRs with 95% CIs, respectively. Results: After adjustment for demographic factors and pre-existing health status, the burn injury cohort had 2.20 times (95% CI 1.86 to 2.61) as many nervous system admissions and 3.25 times the number of days in hospital (95% CI: 2.28 to 4.64) than the uninjured cohort. This increase was found for those who had sustained burns during childhood (