TY - JOUR
T1 - Burden of lower respiratory infections in the Eastern Mediterranean Region between 1990 and 2015
T2 - findings from the Global Burden of Disease 2015 study
AU - GBD 2015 Eastern Mediterranean Region Lower Respiratory Infections Collaborators
AU - Moradi-Lakeh, Maziar
AU - El Bcheraoui, Charbel
AU - Charara, Raghid
AU - Khalil, Ibrahim
AU - Afshin, Ashkan
AU - Kassebaum, Nicholas J.
AU - Collison, Michael
AU - Daoud, Farah
AU - Chew, Adrienne
AU - Krohn, Kristopher J.
AU - Colombara, Danny
AU - Ehrenkranz, Rebecca
AU - Foreman, Kyle J.
AU - Frostad, Joseph
AU - Godwin, William W.
AU - Kutz, Michael
AU - Rao, Puja C.
AU - Reiner, Robert
AU - Troeger, Christopher
AU - Wang, Haidong
AU - Abajobir, Amanuel Alemu
AU - Abbas, Kaja M.
AU - Abera, Semaw Ferede
AU - Abu-Raddad, Laith J.
AU - Adane, Kelemework
AU - Kiadaliri, Aliasghar Ahmad
AU - Ahmadi, Alireza
AU - Ahmed, Muktar Beshir
AU - Al-Eyadhy, Ayman
AU - Alam, Khurshid
AU - Alam, Noor
AU - Alasfoor, Deena
AU - Al-Maskari, Fatma
AU - Al-Raddadi, Rajaa
AU - Alsharif, Ubai
AU - Altirkawi, Khalid A.
AU - Anber, Nahla
AU - Ansari, Hossein
AU - Antonio, Carl Abelardo T.
AU - Anwari, Palwasha
AU - Asayesh, Hamid
AU - Asgedom, Solomon Weldegebreal
AU - Atey, Tesfay Mehari
AU - Arthur Avokpaho, Euripide Frinel G.
AU - Bacha, Umar
AU - Barac, Aleksandra
AU - Bazargan-Hejazi, Shahrzad
AU - Bedi, Neeraj
AU - Bhutta, Zulfiqar A.
AU - Brauer, Michael
AU - Butt, Zahid A.
AU - Castañeda-Orjuela, Carlos A.
AU - Danawi, Hadi
AU - Djalalinia, Shirin
AU - Endries, Aman Yesuf
AU - Eshrati, Babak
AU - Farvid, Maryam S.
AU - Fereshtehnejad, Seyed Mohammad
AU - Fischer, Florian
AU - Garcia-Basteiro, Alberto L.
AU - Gebrehiwot, Kiros Tedla
AU - Gebrehiwot, Tsegaye Tewelde
AU - Hailu, Gessessew Bugssa
AU - Hamadeh, Randah Ribhi
AU - Hambisa, Mitiku Teshome
AU - Hamidi, Samer
AU - Hassanvand, Mohammad Sadegh
AU - Hedayati, Mohammad T.
AU - Horita, Nobuyuki
AU - Husseini, Abdullatif
AU - James, Spencer Lewis
AU - Javanbakht, Mehdi
AU - Jonas, Jost B.
AU - Kasaeian, Amir
AU - Khader, Yousef Saleh
AU - Khan, Ejaz Ahmad
AU - Khan, Gulfaraz
AU - Khoja, Abdullah Tawfih Abdullah
AU - Khubchandani, Jagdish
AU - Kim, Yun Jin
AU - Kissoon, Niranjan
AU - Larson, Heidi J.
AU - Latif, Asma Abdul
AU - Leshargie, Cheru Tesema
AU - Lunevicius, Raimundas
AU - Abd El Razek, Hassan Magdy
AU - Abd El Razek, Mohammed Magdy
AU - Majdzadeh, Reza
AU - Majeed, Azeem
AU - Malekzadeh, Reza
AU - Masoudi Farid, Habibolah
AU - Mehari, Alem
AU - Memish, Ziad A.
AU - Mengistu, Desalegn Tadese
AU - Mezgebe, Haftay Berhane
AU - Nakamura, Sachiko
AU - Oren, Eyal
AU - Mahesh, P. A.
AU - Pourmalek, Farshad
AU - Qorbani, Mostafa
AU - Radfar, Amir
AU - Rafay, Anwar
AU - Rahimi-Movaghar, Vafa
AU - Rai, Rajesh Kumar
AU - Rawaf, David Laith
AU - Rawaf, Salman
AU - Refaat, Amany H.
AU - Rezaei, Satar
AU - Rezai, Mohammad Sadegh
AU - Roba, Hirbo Shore
AU - Roshandel, Gholamreza
AU - Safdarian, Mahdi
AU - Safiri, Saeid
AU - Sahraian, Mohammad Ali
AU - Salamati, Payman
AU - Samy, Abdallah M.
AU - Sartorius, Benn
AU - Sepanlou, Sadaf G.
AU - Shaikh, Masood Ali
AU - Shamsizadeh, Morteza
AU - Shigematsu, Mika
AU - Singh, Jasvinder A.
AU - Sufiyan, Muawiyyah Babale
AU - Tehrani-Banihashemi, Arash
AU - Temsah, Mohamad Hani
AU - Topor-Madry, Roman
AU - Uthman, Olalekan A.
AU - Vollset, Stein Emil
AU - Wadilo, Fiseha
AU - Wakayo, Tolassa
AU - Werdecker, Andrea
AU - Wijeratne, Tissa
AU - Yaghoubi, Mohsen
AU - Yimam, Hassen Hamid
AU - Yonemoto, Naohiro
AU - Younis, Mustafa Z.
AU - Zaki, Maysaa El Sayed
AU - Jumaan, Aisha O.
AU - Vos, Theo
AU - Hay, Simon I.
AU - Naghavi, Mohsen
AU - Mokdad, Ali H.
PY - 2018/5/1
Y1 - 2018/5/1
N2 - Objectives: We used data from the Global Burden of Disease 2015 study (GBD) to calculate the burden of lower respiratory infections (LRIs) in the 22 countries of the Eastern Mediterranean Region (EMR) from 1990 to 2015. Methods: We conducted a systematic analysis of mortality and morbidity data for LRI and its specific etiologic factors, including pneumococcus, Haemophilus influenzae type b, Respiratory syncytial virus, and influenza virus. We used modeling methods to estimate incidence, deaths, and disability-adjusted life-years (DALYs). We calculated burden attributable to known risk factors for LRI. Results: In 2015, LRIs were the fourth-leading cause of DALYs, causing 11,098,243 (95% UI 9,857,095–12,396,566) DALYs and 191,114 (95% UI 170,934–210,705) deaths. The LRI DALY rates were higher than global estimates in 2015. The highest and lowest age-standardized rates of DALYs were observed in Somalia and Lebanon, respectively. Undernutrition in childhood and ambient particulate matter air pollution in the elderly were the main risk factors. Conclusions: Our findings call for public health strategies to reduce the level of risk factors in each age group, especially vulnerable child and elderly populations.
AB - Objectives: We used data from the Global Burden of Disease 2015 study (GBD) to calculate the burden of lower respiratory infections (LRIs) in the 22 countries of the Eastern Mediterranean Region (EMR) from 1990 to 2015. Methods: We conducted a systematic analysis of mortality and morbidity data for LRI and its specific etiologic factors, including pneumococcus, Haemophilus influenzae type b, Respiratory syncytial virus, and influenza virus. We used modeling methods to estimate incidence, deaths, and disability-adjusted life-years (DALYs). We calculated burden attributable to known risk factors for LRI. Results: In 2015, LRIs were the fourth-leading cause of DALYs, causing 11,098,243 (95% UI 9,857,095–12,396,566) DALYs and 191,114 (95% UI 170,934–210,705) deaths. The LRI DALY rates were higher than global estimates in 2015. The highest and lowest age-standardized rates of DALYs were observed in Somalia and Lebanon, respectively. Undernutrition in childhood and ambient particulate matter air pollution in the elderly were the main risk factors. Conclusions: Our findings call for public health strategies to reduce the level of risk factors in each age group, especially vulnerable child and elderly populations.
KW - DALY
KW - Eastern Mediterranean Region
KW - Incidence
KW - Lower respiratory infection
KW - Mortality
UR - http://www.scopus.com/inward/record.url?scp=85026828839&partnerID=8YFLogxK
U2 - 10.1007/s00038-017-1007-0
DO - 10.1007/s00038-017-1007-0
M3 - Article
C2 - 28776246
AN - SCOPUS:85026828839
VL - 63
SP - 97
EP - 108
JO - Sozial-und Praventivmedizin
JF - Sozial-und Praventivmedizin
SN - 0303-8408
IS - Supp. 1
ER -