Bubble cpap versus ventilator cpap in preterm neonates with early onset respiratory distress - A randomized controlled trial

A. Tagare, S.S. Kadam, U.V. Vaidya, A.N. Pandit, Sanjay Patole

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    42 Citations (Scopus)

    Abstract

    Bubble continuous positive airway pressure (BCPAP) is a low cost nasal CPAP delivery system with potential benefits to developing nations. Objective: To compare the efficacy and safety of BCPAP with ventilator-derived CPAP (VCPAP) in preterm neonates with respiratory distress. Methods: In a randomized controlled trial, preterm neonates with Silverman-Anderson score (4 and oxygen requirement (30% within first 6 h of life were randomly allocated to BCPAP or VCPAP. Proportion of neonates with success or failure was compared.Results: In all, 47 of 57 (82.5%) neonates from BCPAP group and 36 of 57 (63.2%) neonates from the VCPAP group completed CPAP successfully (p = 0.03). Neonates who failed CPAP had higher Silverman-Anderson score (p ( 0.01), lower arterial to alveolar oxygenation ratio (p ( 0.05) and needed surfactant more frequently (p ( 0.01).Conclusion: BCPAP has higher success rate than VCPAP for managing preterm neonates with early onset respiratory distress, with comparable safety. © The Author [2013]. Published by Oxford University Press. All rights reserved.
    Original languageEnglish
    Pages (from-to)113-119
    JournalJournal of Tropical Pediatrics
    Volume59
    Issue number2
    DOIs
    Publication statusPublished - 2013

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