Breast cancer tissue diagnosis at terahertz frequencies

Emma Pickwell-Macpherson; Anthony J. Fitzgerald; Vincent P. Wallace

doi:10.1117/12.905116

Breast cancer tissue diagnosis at terahertz frequencies

Emma Pickwell-Macpherson, Anthony J. Fitzgerald, Vincent P. Wallace

Research output: Chapter in Book/Conference paper › Conference paper

5 Citations (Scopus)

Abstract

This paper investigates the feasibility of using terahertz pulsed imaging to detect breast cancer in a reflection imaging geometry. Spectroscopic terahertz data is used to simulate the reflected time domain response functions of healthy fibrous breast tissue and breast cancer tissue. Previously we have looked at the refractive index and absorption coefficient separately to characterize tissues. In this work we investigate their combined effects and identify parameters of the simulated reflected impulse response function and corresponding spectroscopic properties with a view to improving our ability to distinguish between the fibrous and cancer tissues in the breast.

Original language	English
Title of host publication	Optical Interactions with Tissue and Cells XXIII
Editors	E. Duco Jansen, Robert J. Thomas
Place of Publication	San Francisco
Publisher	SPIE
Volume	8221
ISBN (Print)	9780819488640
DOIs	https://doi.org/10.1117/12.905116
Publication status	Published - 2012
Event	Optical Interactions with Tissue and Cells XXIII - San Francisco, United States Duration: 21 Jan 2012 → 26 Jan 2012

Conference

Conference	Optical Interactions with Tissue and Cells XXIII
Country	United States
City	San Francisco
Period	21/01/12 → 26/01/12

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10.1117/12.905116

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title = "Breast cancer tissue diagnosis at terahertz frequencies",

abstract = "This paper investigates the feasibility of using terahertz pulsed imaging to detect breast cancer in a reflection imaging geometry. Spectroscopic terahertz data is used to simulate the reflected time domain response functions of healthy fibrous breast tissue and breast cancer tissue. Previously we have looked at the refractive index and absorption coefficient separately to characterize tissues. In this work we investigate their combined effects and identify parameters of the simulated reflected impulse response function and corresponding spectroscopic properties with a view to improving our ability to distinguish between the fibrous and cancer tissues in the breast.",

keywords = "ex vivo, finite difference time domain simulations, Terahertz spectroscopy",

author = "Emma Pickwell-Macpherson and Fitzgerald, {Anthony J.} and Wallace, {Vincent P.}",

year = "2012",

doi = "10.1117/12.905116",

language = "English",

isbn = "9780819488640",

volume = "8221",

editor = "Jansen, {E. Duco } and Thomas, {Robert J.}",

booktitle = "Optical Interactions with Tissue and Cells XXIII",

publisher = "SPIE",

address = "United States",

note = "Optical Interactions with Tissue and Cells XXIII ; Conference date: 21-01-2012 Through 26-01-2012",

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TY - GEN

T1 - Breast cancer tissue diagnosis at terahertz frequencies

AU - Pickwell-Macpherson, Emma

AU - Fitzgerald, Anthony J.

AU - Wallace, Vincent P.

PY - 2012

Y1 - 2012

N2 - This paper investigates the feasibility of using terahertz pulsed imaging to detect breast cancer in a reflection imaging geometry. Spectroscopic terahertz data is used to simulate the reflected time domain response functions of healthy fibrous breast tissue and breast cancer tissue. Previously we have looked at the refractive index and absorption coefficient separately to characterize tissues. In this work we investigate their combined effects and identify parameters of the simulated reflected impulse response function and corresponding spectroscopic properties with a view to improving our ability to distinguish between the fibrous and cancer tissues in the breast.

AB - This paper investigates the feasibility of using terahertz pulsed imaging to detect breast cancer in a reflection imaging geometry. Spectroscopic terahertz data is used to simulate the reflected time domain response functions of healthy fibrous breast tissue and breast cancer tissue. Previously we have looked at the refractive index and absorption coefficient separately to characterize tissues. In this work we investigate their combined effects and identify parameters of the simulated reflected impulse response function and corresponding spectroscopic properties with a view to improving our ability to distinguish between the fibrous and cancer tissues in the breast.

KW - ex vivo

KW - finite difference time domain simulations

KW - Terahertz spectroscopy

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U2 - 10.1117/12.905116

DO - 10.1117/12.905116

M3 - Conference paper

AN - SCOPUS:84859089021

SN - 9780819488640

VL - 8221

BT - Optical Interactions with Tissue and Cells XXIII

A2 - Jansen, E. Duco

A2 - Thomas, Robert J.

PB - SPIE

CY - San Francisco

T2 - Optical Interactions with Tissue and Cells XXIII

Y2 - 21 January 2012 through 26 January 2012

ER -

Breast cancer tissue diagnosis at terahertz frequencies

Abstract

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