Breast cancer tissue diagnosis at terahertz frequencies

Emma Pickwell-Macpherson, Anthony J. Fitzgerald, Vincent P. Wallace

    Research output: Chapter in Book/Conference paperConference paper

    5 Citations (Scopus)

    Abstract

    This paper investigates the feasibility of using terahertz pulsed imaging to detect breast cancer in a reflection imaging geometry. Spectroscopic terahertz data is used to simulate the reflected time domain response functions of healthy fibrous breast tissue and breast cancer tissue. Previously we have looked at the refractive index and absorption coefficient separately to characterize tissues. In this work we investigate their combined effects and identify parameters of the simulated reflected impulse response function and corresponding spectroscopic properties with a view to improving our ability to distinguish between the fibrous and cancer tissues in the breast.

    Original languageEnglish
    Title of host publicationOptical Interactions with Tissue and Cells XXIII
    EditorsE. Duco Jansen, Robert J. Thomas
    Place of PublicationSan Francisco
    PublisherSPIE
    Volume8221
    ISBN (Print)9780819488640
    DOIs
    Publication statusPublished - 2012
    EventOptical Interactions with Tissue and Cells XXIII - San Francisco, United States
    Duration: 21 Jan 201226 Jan 2012

    Conference

    ConferenceOptical Interactions with Tissue and Cells XXIII
    CountryUnited States
    CitySan Francisco
    Period21/01/1226/01/12

    Fingerprint

    breast
    cancer
    Tissue
    Breast Neoplasms
    Terahertz Imaging
    Breast
    Imaging techniques
    Refractometry
    Impulse response
    impulses
    Refractive index
    absorptivity
    refractivity
    Geometry
    coefficients
    geometry
    Neoplasms

    Cite this

    Pickwell-Macpherson, E., Fitzgerald, A. J., & Wallace, V. P. (2012). Breast cancer tissue diagnosis at terahertz frequencies. In E. D. Jansen, & R. J. Thomas (Eds.), Optical Interactions with Tissue and Cells XXIII (Vol. 8221). [82210M] San Francisco: SPIE. https://doi.org/10.1117/12.905116
    Pickwell-Macpherson, Emma ; Fitzgerald, Anthony J. ; Wallace, Vincent P. / Breast cancer tissue diagnosis at terahertz frequencies. Optical Interactions with Tissue and Cells XXIII. editor / E. Duco Jansen ; Robert J. Thomas. Vol. 8221 San Francisco : SPIE, 2012.
    @inproceedings{7ff595d3582149a6aa1f3d9acc19d7bd,
    title = "Breast cancer tissue diagnosis at terahertz frequencies",
    abstract = "This paper investigates the feasibility of using terahertz pulsed imaging to detect breast cancer in a reflection imaging geometry. Spectroscopic terahertz data is used to simulate the reflected time domain response functions of healthy fibrous breast tissue and breast cancer tissue. Previously we have looked at the refractive index and absorption coefficient separately to characterize tissues. In this work we investigate their combined effects and identify parameters of the simulated reflected impulse response function and corresponding spectroscopic properties with a view to improving our ability to distinguish between the fibrous and cancer tissues in the breast.",
    keywords = "ex vivo, finite difference time domain simulations, Terahertz spectroscopy",
    author = "Emma Pickwell-Macpherson and Fitzgerald, {Anthony J.} and Wallace, {Vincent P.}",
    year = "2012",
    doi = "10.1117/12.905116",
    language = "English",
    isbn = "9780819488640",
    volume = "8221",
    editor = "Jansen, {E. Duco } and Thomas, {Robert J.}",
    booktitle = "Optical Interactions with Tissue and Cells XXIII",
    publisher = "SPIE",
    address = "United States",

    }

    Pickwell-Macpherson, E, Fitzgerald, AJ & Wallace, VP 2012, Breast cancer tissue diagnosis at terahertz frequencies. in ED Jansen & RJ Thomas (eds), Optical Interactions with Tissue and Cells XXIII. vol. 8221, 82210M, SPIE, San Francisco, Optical Interactions with Tissue and Cells XXIII, San Francisco, United States, 21/01/12. https://doi.org/10.1117/12.905116

    Breast cancer tissue diagnosis at terahertz frequencies. / Pickwell-Macpherson, Emma; Fitzgerald, Anthony J.; Wallace, Vincent P.

    Optical Interactions with Tissue and Cells XXIII. ed. / E. Duco Jansen; Robert J. Thomas. Vol. 8221 San Francisco : SPIE, 2012. 82210M.

    Research output: Chapter in Book/Conference paperConference paper

    TY - GEN

    T1 - Breast cancer tissue diagnosis at terahertz frequencies

    AU - Pickwell-Macpherson, Emma

    AU - Fitzgerald, Anthony J.

    AU - Wallace, Vincent P.

    PY - 2012

    Y1 - 2012

    N2 - This paper investigates the feasibility of using terahertz pulsed imaging to detect breast cancer in a reflection imaging geometry. Spectroscopic terahertz data is used to simulate the reflected time domain response functions of healthy fibrous breast tissue and breast cancer tissue. Previously we have looked at the refractive index and absorption coefficient separately to characterize tissues. In this work we investigate their combined effects and identify parameters of the simulated reflected impulse response function and corresponding spectroscopic properties with a view to improving our ability to distinguish between the fibrous and cancer tissues in the breast.

    AB - This paper investigates the feasibility of using terahertz pulsed imaging to detect breast cancer in a reflection imaging geometry. Spectroscopic terahertz data is used to simulate the reflected time domain response functions of healthy fibrous breast tissue and breast cancer tissue. Previously we have looked at the refractive index and absorption coefficient separately to characterize tissues. In this work we investigate their combined effects and identify parameters of the simulated reflected impulse response function and corresponding spectroscopic properties with a view to improving our ability to distinguish between the fibrous and cancer tissues in the breast.

    KW - ex vivo

    KW - finite difference time domain simulations

    KW - Terahertz spectroscopy

    UR - http://www.scopus.com/inward/record.url?scp=84859089021&partnerID=8YFLogxK

    U2 - 10.1117/12.905116

    DO - 10.1117/12.905116

    M3 - Conference paper

    SN - 9780819488640

    VL - 8221

    BT - Optical Interactions with Tissue and Cells XXIII

    A2 - Jansen, E. Duco

    A2 - Thomas, Robert J.

    PB - SPIE

    CY - San Francisco

    ER -

    Pickwell-Macpherson E, Fitzgerald AJ, Wallace VP. Breast cancer tissue diagnosis at terahertz frequencies. In Jansen ED, Thomas RJ, editors, Optical Interactions with Tissue and Cells XXIII. Vol. 8221. San Francisco: SPIE. 2012. 82210M https://doi.org/10.1117/12.905116