Brainstem location of efferent neurones projecting to the guinea pig cochlea

D. Robertson

doi:10.1016/0378-5955(85)90060-7

Brainstem location of efferent neurones projecting to the guinea pig cochlea

D. Robertson

School of Human Sciences

Research output: Contribution to journal › Article › peer-review

100 Citations (Scopus)

Abstract

Retrograde transport of horseradish peroxidase using tetramethylbenzidine as a chromagen was used to map the cell bodies of origin of the efferent projection to the cochlea in the guinea pig. Large numbers of small labelled neurones were found within the body of the lateral superior olivary nucleus (LSO) ipsi-lateral to the injected cochlea. Labelled cells within the contra-lateral LSO were extremely rare (1% or less). Large labelled neurones were found both ipsi-laterally and contra-laterally in the dorsomedial periolivary region, including the medial nucleus of trapezoid body and in the ventral and lateral nuclei of the trapezoid body and the ventral nucleus of lateral lemniscus. It was concluded that some aspects of the distribution of these efferent neurones in the guinea pig are similar to the situation in the rat, whilst others resemble more closely the arrangement found in cat.

Original language	English
Pages (from-to)	79-84
Number of pages	6
Journal	Hearing Research
Volume	20
Issue number	1
DOIs	https://doi.org/10.1016/0378-5955(85)90060-7
Publication status	Published - 1 Jan 1985

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title = "Brainstem location of efferent neurones projecting to the guinea pig cochlea",

abstract = "Retrograde transport of horseradish peroxidase using tetramethylbenzidine as a chromagen was used to map the cell bodies of origin of the efferent projection to the cochlea in the guinea pig. Large numbers of small labelled neurones were found within the body of the lateral superior olivary nucleus (LSO) ipsi-lateral to the injected cochlea. Labelled cells within the contra-lateral LSO were extremely rare (1% or less). Large labelled neurones were found both ipsi-laterally and contra-laterally in the dorsomedial periolivary region, including the medial nucleus of trapezoid body and in the ventral and lateral nuclei of the trapezoid body and the ventral nucleus of lateral lemniscus. It was concluded that some aspects of the distribution of these efferent neurones in the guinea pig are similar to the situation in the rat, whilst others resemble more closely the arrangement found in cat.",

keywords = "cochlea efferent horseradish peroxidase animal cell auditory system brain stem central nervous system cochlear nucleus diagnosis etiology guinea pig motor nerve nonhuman normal value olive peripheral nervous system priority journal Animal Cats Comparative Study Guinea Pigs Hypothalamic Area, Lateral Neurons, Efferent Olivary Nucleus Rats Staining and Labeling Support, Non-U.S. Gov't",

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N2 - Retrograde transport of horseradish peroxidase using tetramethylbenzidine as a chromagen was used to map the cell bodies of origin of the efferent projection to the cochlea in the guinea pig. Large numbers of small labelled neurones were found within the body of the lateral superior olivary nucleus (LSO) ipsi-lateral to the injected cochlea. Labelled cells within the contra-lateral LSO were extremely rare (1% or less). Large labelled neurones were found both ipsi-laterally and contra-laterally in the dorsomedial periolivary region, including the medial nucleus of trapezoid body and in the ventral and lateral nuclei of the trapezoid body and the ventral nucleus of lateral lemniscus. It was concluded that some aspects of the distribution of these efferent neurones in the guinea pig are similar to the situation in the rat, whilst others resemble more closely the arrangement found in cat.

AB - Retrograde transport of horseradish peroxidase using tetramethylbenzidine as a chromagen was used to map the cell bodies of origin of the efferent projection to the cochlea in the guinea pig. Large numbers of small labelled neurones were found within the body of the lateral superior olivary nucleus (LSO) ipsi-lateral to the injected cochlea. Labelled cells within the contra-lateral LSO were extremely rare (1% or less). Large labelled neurones were found both ipsi-laterally and contra-laterally in the dorsomedial periolivary region, including the medial nucleus of trapezoid body and in the ventral and lateral nuclei of the trapezoid body and the ventral nucleus of lateral lemniscus. It was concluded that some aspects of the distribution of these efferent neurones in the guinea pig are similar to the situation in the rat, whilst others resemble more closely the arrangement found in cat.

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Brainstem location of efferent neurones projecting to the guinea pig cochlea

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