Brain-Enriched Coding and Long Non-coding RNA Genes Are Overrepresented in Recurrent Neurodevelopmental Disorder CNVs

Hamid Alinejad-Rokny; Julian I.T. Heng; Alistair R.R. Forrest

doi:10.1016/j.celrep.2020.108307

Brain-Enriched Coding and Long Non-coding RNA Genes Are Overrepresented in Recurrent Neurodevelopmental Disorder CNVs

Hamid Alinejad-Rokny, Julian I.T. Heng, Alistair R.R. Forrest

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

Alinejad-Rokny et al. develop a tool, SNATCNV, to analyze CNV associations in genetic diseases and disorders. By application of SNATCNV to an autism cohort, they generate a high-confidence map of autism-associated CNVs and provide full lists of brain-enriched coding and lncRNA genes.

Original language	English
Article number	108307
Journal	Cell Reports
Volume	33
Issue number	4
DOIs	https://doi.org/10.1016/j.celrep.2020.108307
Publication status	Published - 27 Oct 2020

Access to Document

10.1016/j.celrep.2020.108307Licence: CC BY-NC-ND

Cite this

@article{ea49cb6afccb4f1fbe0aac82addef67d,

title = "Brain-Enriched Coding and Long Non-coding RNA Genes Are Overrepresented in Recurrent Neurodevelopmental Disorder CNVs",

abstract = "Alinejad-Rokny et al. develop a tool, SNATCNV, to analyze CNV associations in genetic diseases and disorders. By application of SNATCNV to an autism cohort, they generate a high-confidence map of autism-associated CNVs and provide full lists of brain-enriched coding and lncRNA genes.",

keywords = "autism spectrum disorder, copy number variation, gene prioritization, lncRNA prioritization, long non-coding RNA, resource for brain enrichment, tissue-specific expression",

author = "Hamid Alinejad-Rokny and Heng, \{Julian I.T.\} and Forrest, \{Alistair R.R.\}",

year = "2020",

month = oct,

day = "27",

doi = "10.1016/j.celrep.2020.108307",

language = "English",

volume = "33",

journal = "Cell Reports",

issn = "2211-1247",

publisher = "Cell Press",

number = "4",

}

TY - JOUR

T1 - Brain-Enriched Coding and Long Non-coding RNA Genes Are Overrepresented in Recurrent Neurodevelopmental Disorder CNVs

AU - Alinejad-Rokny, Hamid

AU - Heng, Julian I.T.

AU - Forrest, Alistair R.R.

PY - 2020/10/27

Y1 - 2020/10/27

N2 - Alinejad-Rokny et al. develop a tool, SNATCNV, to analyze CNV associations in genetic diseases and disorders. By application of SNATCNV to an autism cohort, they generate a high-confidence map of autism-associated CNVs and provide full lists of brain-enriched coding and lncRNA genes.

AB - Alinejad-Rokny et al. develop a tool, SNATCNV, to analyze CNV associations in genetic diseases and disorders. By application of SNATCNV to an autism cohort, they generate a high-confidence map of autism-associated CNVs and provide full lists of brain-enriched coding and lncRNA genes.

KW - autism spectrum disorder

KW - copy number variation

KW - gene prioritization

KW - lncRNA prioritization

KW - long non-coding RNA

KW - resource for brain enrichment

KW - tissue-specific expression

UR - https://www.scopus.com/pages/publications/85094601361

U2 - 10.1016/j.celrep.2020.108307

DO - 10.1016/j.celrep.2020.108307

M3 - Article

C2 - 33113368

AN - SCOPUS:85094601361

SN - 2211-1247

VL - 33

JO - Cell Reports

JF - Cell Reports

IS - 4

M1 - 108307

ER -

Brain-Enriched Coding and Long Non-coding RNA Genes Are Overrepresented in Recurrent Neurodevelopmental Disorder CNVs

Abstract

Access to Document

Other files and links

Fingerprint

Systems Biology of Human Disease

Cite this

Brain-Enriched Coding and Long Non-coding RNA Genes Are Overrepresented in Recurrent Neurodevelopmental Disorder CNVs

Abstract

Access to Document

Other files and links

Fingerprint

Projects

Systems Biology of Human Disease

Cite this