Biomarkers in COPD

Sanjay Ramakrishnan, Mona Bafadhel

Research output: Chapter in Book/Conference paperChapterpeer-review

2 Citations (Scopus)

Abstract

COPD is lagging in the precision medicine race. The term COPD was designed to be an umbrella term, which is intentionally heterogeneous. To help understand the physiology of COPD and better treat our patients, researchers have evaluated many biomarkers in COPD. There are now robust validated biomarkers such as the blood eosinophil count, blood C-reactive protein, plasma fibrinogen, sputum purulence and hypercapnia. However, there is no one biomarker for the various aspects of COPD. Instead, the focus should be on repeatability, evaluation circumstances and validity of candidate biomarkers.

Original languageEnglish
Title of host publicationEncyclopedia of Respiratory Medicine
Place of PublicationSwitzerland
PublisherElsevier
Pages559-572
Number of pages14
Volume2
Edition2nd
ISBN (Electronic)9780081027240
ISBN (Print)9780081027233
DOIs
Publication statusPublished - 1 Jan 2021
Externally publishedYes

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