Bioinformatics tools and databases for analysis of next-generation sequence data

Hong C. Lee, Kaitao Lai, Michał Tadeusz Lorenc, Michael Imelfort, Chris Duran, David Edwards

Research output: Contribution to journalArticlepeer-review

64 Citations (Scopus)


Genome sequencing has been revolutionized by next-generation technologies, which can rapidly produce vast quantities of data at relatively low cost. With data production now no longer being limited, there is a huge challenge to analyse the data flood and interpret biological meaning. Bioinformatics scientists have risen to the challenge and a large number of software tools and databases have been produced and these continue to evolve with this rapidly advancing field. Here, we outline some of the tools and databases commonly used for the analysis of next-generation sequence data with comment on their utility.

Original languageEnglish
Article numberelr037
Pages (from-to)12-24
Number of pages13
JournalBriefings in Functional Genomics
Issue number1
Publication statusPublished - Jan 2012
Externally publishedYes


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