BiCl3-mediated opening of epoxides, a facile route to chlorohydrins or amino alcohols: one reagent, two paths

A. Mccluskey, S.K. Leitch, J. Garner, C.E. Caden, T.A. Hill, L.R. Odell, Scott Stewart

Research output: Contribution to journalArticlepeer-review

41 Citations (Scopus)

Abstract

Opening of epoxides can be an effective means by which a variety of functional groups can be incorporated. In this letter, we outline how variation of conditions, in particular, that of solvent and concentration, give rise to different products using the Lewis acid catalyst BiCl3. (c) 2005 Elsevier Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)8229-8232
JournalTetrahedron Letters
Volume46
Issue number21
DOIs
Publication statusPublished - 2005

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