Azithromycin inhibits mucin secretion, mucous metaplasia, airway inflammation and airways hyperresponsiveness in mice exposed to house dust mite extract

Tracy S Mann; Alexander N Larcombe; Kimberley C W Wang; Danial Shamsuddin; Katherine R Landwehr; Peter B Noble; Peter J Henry

doi:10.1152/ajplung.00487.2021

Azithromycin inhibits mucin secretion, mucous metaplasia, airway inflammation and airways hyperresponsiveness in mice exposed to house dust mite extract

Research output: Contribution to journal › Article › peer-review

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Original language	English
Pages (from-to)	L683-L698
Journal	American Journal of Physiology - Lung Cellular and Molecular Physiology
Volume	322
Issue number	5
Early online date	29 Mar 2022
DOIs	https://doi.org/10.1152/ajplung.00487.2021
Publication status	Published - May 2022

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1152/ajplung.00487.2021

Mann, et al., 2022 Azithromycin inhibits mucin secretionAccepted author manuscript, 4.3 MB

Investigating the effects of macrolides on excessive synthesis and secretion of airway mucins using novel ex vivo and in vivo approaches
Henry, P. (Investigator 01) & Larcombe, A. (Investigator 02)
NHMRC National Health and Medical Research Council
1/01/18 → 31/12/21
Project: Research

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Mann, T. S., Larcombe, A. N., Wang, K. C. W., Shamsuddin, D., Landwehr, K. R., Noble, P. B., & Henry, P. J. (2022). Azithromycin inhibits mucin secretion, mucous metaplasia, airway inflammation and airways hyperresponsiveness in mice exposed to house dust mite extract. American Journal of Physiology - Lung Cellular and Molecular Physiology, 322(5), L683-L698. https://doi.org/10.1152/ajplung.00487.2021

@article{28c220c288484d7e87b479c909c808d4,

title = "Azithromycin inhibits mucin secretion, mucous metaplasia, airway inflammation and airways hyperresponsiveness in mice exposed to house dust mite extract",

author = "Mann, \{Tracy S\} and Larcombe, \{Alexander N\} and Wang, \{Kimberley C W\} and Danial Shamsuddin and Landwehr, \{Katherine R\} and Noble, \{Peter B\} and Henry, \{Peter J\}",

year = "2022",

month = may,

doi = "10.1152/ajplung.00487.2021",

language = "English",

volume = "322",

pages = "L683--L698",

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publisher = "American Physiological Society",

number = "5",

}

Mann, TS, Larcombe, AN , Wang, KCW, Shamsuddin, D, Landwehr, KR , Noble, PB & Henry, PJ 2022, 'Azithromycin inhibits mucin secretion, mucous metaplasia, airway inflammation and airways hyperresponsiveness in mice exposed to house dust mite extract', American Journal of Physiology - Lung Cellular and Molecular Physiology, vol. 322, no. 5, pp. L683-L698. https://doi.org/10.1152/ajplung.00487.2021

Azithromycin inhibits mucin secretion, mucous metaplasia, airway inflammation and airways hyperresponsiveness in mice exposed to house dust mite extract. / Mann, Tracy S; Larcombe, Alexander N ; Wang, Kimberley C W et al.
In: American Journal of Physiology - Lung Cellular and Molecular Physiology, Vol. 322, No. 5, 05.2022, p. L683-L698.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Azithromycin inhibits mucin secretion, mucous metaplasia, airway inflammation and airways hyperresponsiveness in mice exposed to house dust mite extract

AU - Mann, Tracy S

AU - Larcombe, Alexander N

AU - Wang, Kimberley C W

AU - Shamsuddin, Danial

AU - Landwehr, Katherine R

AU - Noble, Peter B

AU - Henry, Peter J

PY - 2022/5

Y1 - 2022/5

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DO - 10.1152/ajplung.00487.2021

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SP - L683-L698

JO - American Journal of Physiology - Lung Cellular and Molecular Physiology

JF - American Journal of Physiology - Lung Cellular and Molecular Physiology

IS - 5

ER -

Mann TS, Larcombe AN , Wang KCW, Shamsuddin D, Landwehr KR , Noble PB et al. Azithromycin inhibits mucin secretion, mucous metaplasia, airway inflammation and airways hyperresponsiveness in mice exposed to house dust mite extract. American Journal of Physiology - Lung Cellular and Molecular Physiology. 2022 May;322(5):L683-L698. Epub 2022 Mar 29. doi: 10.1152/ajplung.00487.2021

Azithromycin inhibits mucin secretion, mucous metaplasia, airway inflammation and airways hyperresponsiveness in mice exposed to house dust mite extract

UN SDGs

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Projects

Investigating the effects of macrolides on excessive synthesis and secretion of airway mucins using novel ex vivo and in vivo approaches

Cite this